Tyrell Cartwright
About
I completed my undergraduate pre-medical degree in Biology with a minor in chemistry (BSc.) with distinction at the College of the Bahamas in 2012. From here I decided to become more involved in research and completed a Masters of Research in Immunobiology at Newcastle University in 2014. Having enjoyed this experience I applied for and received a Newcastle University Overseas Research Studentship Award and with this I am currently persuing a PhD in the Fibrosis Research Group under the supervision of Prof. Derek Mann and Dr Caroline Wilson.
My Project involves understanding the structural mechanisms of the p50:p50:HDAC1 interaction as well as the control of p50 dimerization with the future goal of subunit specific therapeutics for cancer and Fibrosis as well as other diseases modulated by inflammation.
Education
- Masters of Research in Immunobiology - Newcastle University
- BSc in Biology (with Distinction) -University of the Bahamas
Publications
- 2018 - Cartwright T, Worrell J, Marchetti L, Dowling C, Knox A, Kiely P, Mann J, Mann D, Wilson C - HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression
- 2016 - Cartwright T, Perkins ND, Wilson CL (2016) NFKB1: a suppressor of inflammation, ageing and cancer.
- 2016 - Borthwick LA, Suwara MI, Carnell SC, Green NJ, Mahida R, Dixon D, Gillespie CS, Cartwright TN, Horabin J, Walker A, Olin E, Rangar M, Gardner A, Mann J, Corris PA, Mann DA, Fisher AJ. Pseudomonas aeruginosa induced airway epithelial injury drives fibroblast activation: a mechanism in chronic lung allograft dysfunction.