Newcastle Fibrosis Research Group

The Newcastle Fibrosis Research Group is a top-level multi-disciplinary research group of Newcastle University highly experienced in the underlying mechanisms of fibrosis in liver, lung, kidney, heart, skin and joints.

Our Research

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Public Engagement

As part of a higher education institution, engaging ourselves with society is a key priority. Fibrotic diseases involve complex mechanisms which we think should be understandable by everyone. Teaching and wide diffusion knowledge about Fibrosis is one of our leading missions.

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News & Events

A new NFRG review by Teresa Borrello published in the British Journal of Pharmacology

Chronic liver diseases: From development to novel pharmacological therapies

A team effort and collaborative work led by Jack Leslie results in a new publication in Gut

CXCR2 inhibition enables NASH- HCC immunotherapy

A new review by NFRG by Jack Leslie, Daniel Geh and Derek Mann in Journal of Hepatology

Metabolic dysfunction and cancer in HCV: shared pathways and mutual interactions

A new NFRG review by Fiona Oakley published in Nature Reviews Gastroenterology & Hepatology

Interrogating mechanisms of liver fibrosis with omics

A new NFRG review by Daniel Geh, Jack Leslie and Derek Mann published in Nature Reviews Gastroenterology & Hepatology

Neutrophils as potential therapeutic targets in hepatocellular carcinoma

A new book chapter in the Encyclopaedia of Respiratory Medicine By Will Reilly, Rachel Burgoyne and Lee Borthwick

The Role of Epithelial Damage in the Pulmonary Immune Response

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