Newcastle Fibrosis Research Group

The Newcastle Fibrosis Research Group is a top-level multi-disciplinary research group of Newcastle University highly experienced in the underlying mechanisms of fibrosis in liver, lung, kidney, heart, skin and joints.

Our Research

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Public Engagement

As part of a higher education institution, engaging ourselves with society is a key priority. Fibrotic diseases involve complex mechanisms which we think should be understandable by everyone. Teaching and wide diffusion knowledge about Fibrosis is one of our leading missions.

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News & Events

NFRG Work led By Lee Borthwick published in JCI Insight

FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

Duchenne UK funds a new £163,637 grant to NFRG

Objective: helping to improve the success rate of clinical trials to fight Duchenne Muscular Dystrophy

Lee Borthwick contributes to publication in PNAS with the Universities of Manchester, Oxford, UCL, and Toronto

The circadian clock protein REVERBα inhibits pulmonary fibrosis development

Jelena Mann awarded the Roy Cameron Medal

Prof Mann gave the 2019 Roy Cameron Lecture "Epigenetics and Liver Fibrosis" at the Royal College of Pathologists

A new NFRG review focusing on PCLS published in Current Opinion in Pharmacology

Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy

NFRG Collective work leads to a new paper in Gastroenterology in November 2019

Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells

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