Newcastle Fibrosis Research Group

Newcastle Fibrosis Research Group

The Newcastle Fibrosis Research Group is a top-level multi-disciplinary research group of Newcastle University highly experienced in the underlying mechanisms of fibrosis in liver, lung, kidney, heart, skin and joints.

Our Research

Public Engagement

As part of a higher education institution, engaging ourselves with society is a key priority. Fibrotic diseases involve complex mechanisms which we think should be understandable by everyone. Teaching and wide diffusion knowledge about Fibrosis is one of our leading missions.

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News & Events

NFRG Work led By Lee Borthwick published in JCI Insight

FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

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Duchenne UK funds a new £163,637 grant to NFRG

Objective: helping to improve the success rate of clinical trials to fight Duchenne Muscular Dystrophy

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Lee Borthwick contributes to publication in PNAS with the Universities of Manchester, Oxford, UCL, and Toronto

The circadian clock protein REVERBα inhibits pulmonary fibrosis development

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Jelena Mann awarded the Roy Cameron Medal

Prof Mann gave the 2019 Roy Cameron Lecture "Epigenetics and Liver Fibrosis" at the Royal College of Pathologists

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A new NFRG review focusing on PCLS published in Current Opinion in Pharmacology

Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy

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NFRG Collective work leads to a new paper in Gastroenterology in November 2019

Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells

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