Julie Worrell
About
I completed my undergraduate degree in Pharmacology in 2011 at University College Dublin, Ireland. In 2011 I was accepted into the Molecular Medicine Ireland Clinical and Translational Research Scholars program a unique cross-institutional PhD program. This PhD program included both taught and research components in addition to an industry placement at UCB pharma in Slough, UK.
My PhD project was completed under the supervision of Prof. Michael Keane at the Conway Institute, University College Dublin. My project focused on the role of the chemokine receptor CXCR3 in idiopathic pulmonary fibrosis and had a strong translational focus.
I joined the Fibrosis Research Group at Newcastle University in September 2015 as a Research Associate. This is a 3 year post funded by Arthritis Research UK and focuses on the role of a molecule called c-Rel in the production of scar tissue.
Education
- PhD – The Role and Regulation of the CXCR3 Receptor in Pulmonary Fibrosis- University College Dublin.
- BSc- Pharmacology- University College Dublin.
Publications
- 2018 - Cartwright T, Worrell J, Marchetti L, Dowling C, Knox A, Kiely P, Mann J, Mann D, Wilson C - HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression
- 2015 - Sarah L. O'Beirne, Sinead M. Walsh, Aurélie Fabre, Carlota Reviriego, Julie C. Worrell, Ian P. Counihan, Robert V. Lumsden, Jennifer Cramton-Barnes, John A. Belperio, Seamas C. Donnelly, Denise Boylan, Joëlle, Marchal-Sommé, Rosemary Kane and Michael P. Keane - CXCL9 Regulates TGF-b1-Induced Epithelial to Mesenchymal Transition in Human Alveolar Epithelial Cells;
- 2015 - Robert V. Lumsden, Julie C. Worrell, Denise Boylan, Sinead M. Walsh, Jennifer Cramton, Ian Counihan, Sarah O’Beirne, Maria Fe Medina, Jack Gauldie, Aurelie Fabre, Seamas C. Donnelly, Rosemary Kane, and Michael P. Keane - Modulation of pulmonary fibrosis by IL-13R2
- 2014 - Jennifer C. Barnes, Robert V. Lumsden, Julie Worrell, Ian P. Counihan1, Sarah L. O’Beirne, John A. Belperio, Aurelie Fabre, Seamas C. Donnelly, Denise Boylan, Rosemary Kane, and Michael P. Keane - CXCR3 Requirement for the Interleukin-13–Mediated Up-Regulation of Interleukin-13Ra2 in Pulmonary Fibroblasts;