Dynamic neuronal interactions along visuomotor pathways

Location(s): CNRS & Aix-Marseille University, Marseille, France. 

Supervisors: Dr T Brochier, Dr A Brovelli, Dr A Riehle

The cortical substrates for hand movement control include multiple parieto-frontal pathways for the feedforward (bottom-up) transformation of visual inputs into appropriate motor commands. Anatomical evidence shows that connectivity patterns across occipito-parieto-frontal circuits are largely reciprocal. However, the functional relevance of the dynamic processing of motor information in parietal and visual areas remains debated. To address this issue, our project will analyze the cortical interactions occurring between discrete cortical structures in macaque monkeys performing complex visuomotor tasks. The dynamics of visuomotor-related directed cortico-cortical interactions will be investigated using information theory approaches and Granger causality analyses. In collaboration with ESR 1 and 3, we will also investigate interactions along the entire visuo-motor pathways in marmoset monkeys.

Behavioural paradigm: continuous arm reaching movements towards visual targets in 2D plane.

Recording and stimulation techniques: Multi-electrode array recordings of spike and LFPs (macaques) and ECoG (marmoset).

Planned Secondment(s):

  • German Primate Center (DPZ)
  • French National Centre for Scientific Research (CNRS)

Contact: email Dr Brochier

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