BNS Undergrad Summer Placement Poster Prize

Brigid Davidson won a poster prize at the BNS Undergrad Summer Placement Poster Event for her vacation project in Jon's lab

Last modified: Wed, 20 Nov 2019 09:10:45 GMT

MRC CDA for Suzanne Madgwick!

Fantastic news: Suzanne Madgwick has been granted an MRC Career Development Award to continue her work on the origins of aneuploidy in oocytes.

Last modified: Thu, 31 Oct 2019 09:32:44 GMT

ICaMB Away Day prize for Beccy

Well done to Beccy Harris from Jon's lab who won the prize for best poster at the ICaMB Away Day on 16th October

Last modified: Wed, 20 Nov 2019 09:06:56 GMT

ICaMB Away Day, 16th October

Excellent presentations from Ben Wetherall, Jack Martin and Mark Levasseur of the CDB Group at the last ever ICaMB Away Day

Last modified: Wed, 20 Nov 2019 09:21:17 GMT

Nik Watson awarded his PhD

Nik Watson from Jon's lab has been awarded his PhD, and is now off to Copenhagen for a post-doc

Last modified: Thu, 31 Oct 2019 10:51:37 GMT

Jianquan Li, PhD!

Jianquan Li from Jun-yong’s lab has successfully defended his PhD thesis, and is now off to work in the Intensive Care Unit, Guizhou Provincial People’s Hospital, Guiyang, People’s Republic of China.

Last modified: Thu, 31 Oct 2019 10:29:04 GMT

New paper from Jun-yong Huang's lab

A new paper from Jianquan Li and others in Jun-yong’s lab shows that M2I-1, the first small molecule identified to disrupt CDC20-MAD2 interaction, enhances the sensitivity of cancer cells to anti-mitotic drugs

Last modified: Tue, 18 Jun 2019 10:55:41 BST

Paper on new mitotic histone modification published

A collaboration with Markus Seibert and others in Lino Schmitz's lab at Justus-Liebig-University, Giessen, reveals new mitotic phosphorylation site and the kinases responsible.

Last modified: Mon, 25 Feb 2019 10:41:11 GMT

New paper on Cdk1-Cyclin B1 regulation in meiosis

Suzanne Madgwick's paper in Dev. Cell, together with Mark Levasseur and Chris Thomas, shows how extra Cyclin B1 is regulated in meiosis I to ensure accurate chromosome segregation.

Last modified: Mon, 11 Feb 2019 17:45:52 GMT

New paper from Owen's lab in Nature Communications

A new paper from James Dunce and others in Owen Davies' lab shows the structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.

Last modified: Mon, 11 Feb 2019 17:32:58 GMT

New paper on selective CDK1/2 inhibition

A team including Daniel Wood, Svitlana Korolchuk, Mathew Martin and Martin Noble show how "Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition"

Last modified: Thu, 31 Oct 2019 09:50:03 GMT

Leading Edge project with local school

In May, a group of pupils from Sandhill View Academy, led by Dr. Glen Bunn, carried out a “Leading Edge Project” in Jun-Yong Huang’s lab with the help of Nanmao Dang.

Last modified: Mon, 05 Nov 2018 17:34:04 GMT

Telomere Network UK Meeting

The TenUK Meeting on telomeres was held on 11th and 12th September in Newcastle, hosted by David Lydall (Newcastle), Alessandro Bianchi (Sussex) and Nicola Royle (Leicester).

Last modified: Mon, 03 Dec 2018 14:17:25 GMT

Cell Division Biology Summer Symposium

Our second Cell Division Biology Symposium was a great event, with inspiring talks from our external speakers, Andrea Musacchio, Helder Maiato and Andrew Wood. Excellent presentations from our own students, postdocs and PIs too, of course!

Last modified: Tue, 31 Jul 2018 18:10:16 BST

GRC Molecular Mechanisms and Regulation of Meiosis Across Species

Owen gave a talk at the recent meiosis Gordon Research Conference, and his joint PhD student with Amy McQueen, Chandni Ravindan, spoke at the preceding Gordon Research Seminar.

Last modified: Tue, 31 Jul 2018 18:14:48 BST

James Dunce's paper on SYCP1 paper is out

The paper, in Nature Structural and Molecular Biology, describes the structure of SYCP1 and its role in synaptonemal complex structure.

Last modified: Fri, 05 Oct 2018 09:49:34 BST

Onur Sen's paper on SiR-Hoechst published

Onur's paper, which shows that the live cell DNA dye SiR-Hoechst is not as benign as one would hope, has been published.

Last modified: Tue, 19 Jun 2018 14:47:48 BST

Grant for Josana!

Fantastic news: Josana Rodriguez has been awarded a New Investigator project grant from the BBSRC.

Last modified: Tue, 24 Apr 2018 09:12:52 BST

Save the Date - CDB Spring Meeting

The first of what we hope will be quarterly meetings of the whole CDB Group will take place on the top floor of the Business School on the afternoon of 26th March.

Last modified: Tue, 27 Feb 2018 10:48:15 GMT

Chris Thomas, PhD!

Chris Thomas from Suzanne's lab has successfully defended his PhD thesis, and is now off to work in Melina Schuh's lab in Göttingen

Last modified: Tue, 24 Apr 2018 09:21:34 BST

New paper on Hsp90 control of G1 CDKs

Stephen Hallet and Martyna Pastok in Jane's lab, working with collaborators at the Genome Damage and Stability Centre at Sussex, show how chaperones control Cdk activity

Last modified: Thu, 31 Oct 2019 09:44:32 GMT

BBSRC grant awarded

A BBSRC Project Grant awarded to support Diana Papini's work on the role of Aurora B in anaphase in Jon Higgins' lab began on 1st October.

Last modified: Wed, 11 Oct 2017 15:21:58 BST

EMBO Meiosis Meeting in Hvar, Croatia

Interesting talks at the EMBO Meiosis Meeting 2017, including from Owen!

Last modified: Fri, 15 Sep 2017 10:05:29 BST

Top marks and scholarship for Natalija Stepurko

Natalija, undergraduate research assistant in Owen's lab, obtained the highest Stage 2 mark in all biomedical subjects, and has spent the summer on a prestigious Amgen Scholarship at the University of Cambridge.

Last modified: Fri, 15 Sep 2017 10:25:10 BST

New paper from Josana's lab in Developmental Cell

A new paper from Josana's lab describing how aPKC cycles between functionally distinct PAR protein assemblies to drive cell polarity has just been published online in Developmental Cell

Last modified: Mon, 07 Aug 2017 11:10:10 BST

Cell Division Biology Retreat

The weather held for the Cell Division Biology Group Retreat at the Dove Marine Laboratory overlooking the beach in Cullercoats.

Last modified: Wed, 12 Jul 2017 10:24:43 BST

Outreach: "Leading Edge" project

In April, a group of pupils from St. Anthony’s Girls’ Catholic Academy led by Dr. Gillian Emery successfully conducted their “Leading Edge Project” in Jun-Yong Huang’s lab with the help of MRes student Lucy Barnsby.

Last modified: Wed, 14 Jun 2017 11:02:06 BST

Shugoshin-2 paper in Current Biology

In collaboration with Kim Nasmyth's lab, Randi Ballesteros in Mary's lab has helped explain how APC/C-Cdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes

Last modified: Thu, 31 Oct 2019 10:39:10 GMT

New paper from Jun-yong's lab

Jianquan Li, Nanmao Dang and Daniel Wood from Jun-yong's lab have a new paper published in Scientific Reports describing the kinetochore-dependent and -independent formation of the CDC20-MAD2 complex in individual cells.

Last modified: Tue, 15 Aug 2017 12:41:58 BST

Higgins and Madgwick Lab New Year Dinner

The Higgins and Madgwick labs took advantage of Newcastle's Restaurant Week and enjoyed a late New Year dinner at Blackfriars

Last modified: Mon, 27 Feb 2017 17:52:11 GMT

Randy Ballesteros defends his PhD

Randy from Mary's lab successfully defended his PhD thesis on 11th January.

Last modified: Mon, 27 Feb 2017 18:01:52 GMT

Jonny McHugh wins poster prize

Congratulations to Jonny McHugh, a Wellcome Trust summer vacation student in the labs of Alex Laude (Bioimaging Unit) and Jon Higgins, who won a Biomedical Sciences prize for his poster describing the project.

Last modified: Fri, 07 Apr 2017 10:28:34 BST

CDB Interlab Christmas Meal

CDB Interlab Meeting participants enjoyed a Christmas meal at As You Like It on December 6th.

Last modified: Fri, 16 Dec 2016 10:26:17 GMT

Outreach: Science Uncovered

The "Science Uncovered" evening at the Great North Museum included an opportunity for the public to tour the Bioimaging Unit and find out about cell division from CDB member Diana Papini.

Last modified: Mon, 07 Nov 2016 10:39:09 GMT

Bio-Imaging Outreach Event at Centre for Life

Members of the CDB Group helped out with Cell Division Day during the "Meet the Scientist" event run by Newcastle University's Bio-Imaging Unit at the International Centre for Life

Last modified: Tue, 09 Aug 2016 11:14:08 BST

Inaugural Cell Division Biology Symposium 2016

Our first Cell Division Biology Symposium was a success and there was a consensus that we should make it a recurring event.

Last modified: Wed, 27 Jul 2016 09:38:34 BST

Beccy Harris wins undergraduate prize

Congratulations to Beccy Harris who received the highest marks in Biochemistry for her undergraduate project in Jon Higgins's lab, and won the Gus Lienhard Prize for Biochemistry for the highest overall mark on her degree course.

Last modified: Fri, 15 Jul 2016 14:07:51 BST

PNT paper from the Herbert lab in Nature

A study from Mary Herbert's lab describing an improved procedure for pronuclear transfer to prevent mitochondrial disease is published in Nature.

Last modified: Thu, 09 Jun 2016 10:01:09 BST

Josana speaks at European Worm Meeting

Josana Rodriguez's talk was well-received at the recent European Worm Meeting in Berlin.

Last modified: Thu, 09 Jun 2016 14:16:42 BST

Inaugural Cell Division Biology Symposium 2016

An exciting line up of external speakers for our first Cell Division Biology Symposium on July 4th has been finalised: Iain Cheeseman, Marie-Helene Verlhac, Nate Goehring and Julie Welburn.

Last modified: Tue, 07 Jun 2016 22:23:09 BST

CDB Christmas Lunch

After the interlab meeting this week, some of the CDB group headed out for a Christmas lunch in town

Last modified: Wed, 16 Dec 2015 10:10:00 GMT

MRes Programme Prize for 2014/2015

Daniel Wood, who carried out his project in Jun-Yong Huang’s lab, has won the MRes Student Prize for 2014/2015.

Last modified: Wed, 25 Nov 2015 15:09:48 GMT

ICaMB Away Day 2015

This year's ICaMB Away Day is being held at the Tyneside Cinema. Diana Papini and Suzanne Madgwick will be speaking.

Last modified: Fri, 16 Oct 2015 14:18:17 BST

Covalent CDK inhibitor discovered

Jane Endicott's lab, in collaboration with Prof Griffin and others at the NICR, have designed and tested the first selective irreversible inhibitor of Cdk2.

Last modified: Fri, 09 Oct 2015 14:01:28 BST

MRes Poster Prize 2015

Matthew Ratcliff from Owen Davies' lab wins the prize for the best MRes poster

Last modified: Wed, 09 Sep 2015 09:54:46 BST

Undergraduate Project Prize 2015

Vincentius Aji Jatikusumo wins the ICaMB prize for his undergraduate lab project carried out in Owen Davies' lab.

Last modified: Wed, 09 Sep 2015 10:11:59 BST

EU Horizon 2020 Grant for Mary Herbert

Mary Herbert and collaborators have been awarded a major Horizon 2020 grant to study "The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem"

Last modified: Mon, 07 Sep 2015 15:10:07 BST

EMBO Conference on Meiosis 2015

Three CDB Group members will present at the upcoming EMBO Meiosis meeting in Oxford.

Last modified: Mon, 10 Aug 2015 15:02:32 BST

Diana Papini's TD-60 paper in Nature Communications

Diana's paper describing GEF activity for TD-60 in mitosis is published.

Last modified: Tue, 11 Aug 2015 13:36:55 BST

Jon Higgins becomes a Wellcome Trust Investigator

Prof Jon Higgins has been awarded a prestigious Wellcome Trust Investigator Award.

Last modified: Tue, 04 Aug 2015 16:11:02 BST

LSI - Zhejiang University visit

A delegation from the Life Sciences Institute (LSI) at Zhejiang University, China, visited in May 2015

Last modified: Wed, 15 Jul 2015 21:13:03 BST

British Meiosis Meeting in Newcastle

The British Meiosis Meeting was held in Newcastle from February 23-24th, organised by Mary Herbert, Owen Davies, Suzanne Madgwick, Raveen Sandher, Aïcha Metchat, and Mahdi Lamb.

Last modified: Mon, 27 Jul 2015 13:53:41 BST

New paper from Endicott and Noble labs

A new paper in Nature Communications from Jane Endicott's and Martin Noble's labs describes the first structure of the essential mitotic kinase Cdk1-Cyclin B, and its interaction with the regulator Cks1.

Last modified: Tue, 04 Aug 2015 16:11:05 BST

Davies Group: new publication in Nature Structural and Molecular Biology

CtIP tetramer assembly is required for DNA-end resection and repair

Last modified: Fri, 17 Jul 2015 13:31:39 BST

Owen Davies becomes a Sir Henry Dale Fellow

Congratulations to Owen Davies, who has been made a Sir Henry Dale Fellow, funded by the Royal Society and the Wellcome Trust.

Last modified: Mon, 10 Aug 2015 15:53:35 BST

Paper in eLife from Owen Davies

Owen Davies' work leads to a new model for the structure of the synaptonemal complex that holds homologous chromosomes together in meiosis.

Last modified: Tue, 04 Aug 2015 16:10:56 BST

Royal Society Wolfson Research Merit Award for Jon Higgins

Jon Higgins has received a reward to facilitate his move to Newcastle from the Brigham and Women's Hospital, Harvard Medical School.

Last modified: Tue, 04 Aug 2015 16:10:51 BST

Paper in EMBO Reports from Higgins lab

A collaborative study between the Higgins lab (Newcastle) and Fangwei Wang's lab at the LSI, Zhejiang University, China, shows how Polo-like kinase regulates Haspin in mitosis.

Last modified: Tue, 04 Aug 2015 16:10:53 BST

New Endicott and Noble paper

Different activation states of a particular Cyclin-dependent kinase may differ from each other as much as different CDKs in the same activation state.

Last modified: Mon, 27 Jul 2015 13:43:12 BST