News
BNS Undergrad Summer Placement Poster Prize
Brigid Davidson won a poster prize at the BNS Undergrad Summer Placement Poster Event for her vacation project in Jon's lab
Last modified: Wed, 20 Nov 2019 09:10:45 GMT
MRC CDA for Suzanne Madgwick!
Fantastic news: Suzanne Madgwick has been granted an MRC Career Development Award to continue her work on the origins of aneuploidy in oocytes.
Last modified: Thu, 31 Oct 2019 09:32:44 GMT
ICaMB Away Day prize for Beccy
Well done to Beccy Harris from Jon's lab who won the prize for best poster at the ICaMB Away Day on 16th October
Last modified: Wed, 20 Nov 2019 09:06:56 GMT
ICaMB Away Day, 16th October
Excellent presentations from Ben Wetherall, Jack Martin and Mark Levasseur of the CDB Group at the last ever ICaMB Away Day
Last modified: Wed, 20 Nov 2019 09:21:17 GMT
Nik Watson awarded his PhD
Nik Watson from Jon's lab has been awarded his PhD, and is now off to Copenhagen for a post-doc
Last modified: Thu, 31 Oct 2019 10:51:37 GMT
Jianquan Li, PhD!
Jianquan Li from Jun-yong’s lab has successfully defended his PhD thesis, and is now off to work in the Intensive Care Unit, Guizhou Provincial People’s Hospital, Guiyang, People’s Republic of China.
Last modified: Thu, 31 Oct 2019 10:29:04 GMT
New paper from Jun-yong Huang's lab
A new paper from Jianquan Li and others in Jun-yong’s lab shows that M2I-1, the first small molecule identified to disrupt CDC20-MAD2 interaction, enhances the sensitivity of cancer cells to anti-mitotic drugs
Last modified: Tue, 18 Jun 2019 10:55:41 BST
Paper on new mitotic histone modification published
A collaboration with Markus Seibert and others in Lino Schmitz's lab at Justus-Liebig-University, Giessen, reveals new mitotic phosphorylation site and the kinases responsible.
Last modified: Mon, 25 Feb 2019 10:41:11 GMT
New paper on Cdk1-Cyclin B1 regulation in meiosis
Suzanne Madgwick's paper in Dev. Cell, together with Mark Levasseur and Chris Thomas, shows how extra Cyclin B1 is regulated in meiosis I to ensure accurate chromosome segregation.
Last modified: Mon, 11 Feb 2019 17:45:52 GMT
New paper from Owen's lab in Nature Communications
A new paper from James Dunce and others in Owen Davies' lab shows the structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.
Last modified: Mon, 11 Feb 2019 17:32:58 GMT
New paper on selective CDK1/2 inhibition
A team including Daniel Wood, Svitlana Korolchuk, Mathew Martin and Martin Noble show how "Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition"
Last modified: Thu, 31 Oct 2019 09:50:03 GMT
Leading Edge project with local school
In May, a group of pupils from Sandhill View Academy, led by Dr. Glen Bunn, carried out a “Leading Edge Project” in Jun-Yong Huang’s lab with the help of Nanmao Dang.
Last modified: Mon, 05 Nov 2018 17:34:04 GMT
Telomere Network UK Meeting
The TenUK Meeting on telomeres was held on 11th and 12th September in Newcastle, hosted by David Lydall (Newcastle), Alessandro Bianchi (Sussex) and Nicola Royle (Leicester).
Last modified: Mon, 03 Dec 2018 14:17:25 GMT
Cell Division Biology Summer Symposium
Our second Cell Division Biology Symposium was a great event, with inspiring talks from our external speakers, Andrea Musacchio, Helder Maiato and Andrew Wood. Excellent presentations from our own students, postdocs and PIs too, of course!
Last modified: Tue, 31 Jul 2018 18:10:16 BST
GRC Molecular Mechanisms and Regulation of Meiosis Across Species
Owen gave a talk at the recent meiosis Gordon Research Conference, and his joint PhD student with Amy McQueen, Chandni Ravindan, spoke at the preceding Gordon Research Seminar.
Last modified: Tue, 31 Jul 2018 18:14:48 BST
James Dunce's paper on SYCP1 paper is out
The paper, in Nature Structural and Molecular Biology, describes the structure of SYCP1 and its role in synaptonemal complex structure.
Last modified: Fri, 05 Oct 2018 09:49:34 BST
Onur Sen's paper on SiR-Hoechst published
Onur's paper, which shows that the live cell DNA dye SiR-Hoechst is not as benign as one would hope, has been published.
Last modified: Tue, 19 Jun 2018 14:47:48 BST
Grant for Josana!
Fantastic news: Josana Rodriguez has been awarded a New Investigator project grant from the BBSRC.
Last modified: Tue, 24 Apr 2018 09:12:52 BST
Save the Date - CDB Spring Meeting
The first of what we hope will be quarterly meetings of the whole CDB Group will take place on the top floor of the Business School on the afternoon of 26th March.
Last modified: Tue, 27 Feb 2018 10:48:15 GMT
Chris Thomas, PhD!
Chris Thomas from Suzanne's lab has successfully defended his PhD thesis, and is now off to work in Melina Schuh's lab in Göttingen
Last modified: Tue, 24 Apr 2018 09:21:34 BST
New paper on Hsp90 control of G1 CDKs
Stephen Hallet and Martyna Pastok in Jane's lab, working with collaborators at the Genome Damage and Stability Centre at Sussex, show how chaperones control Cdk activity
Last modified: Thu, 31 Oct 2019 09:44:32 GMT
BBSRC grant awarded
A BBSRC Project Grant awarded to support Diana Papini's work on the role of Aurora B in anaphase in Jon Higgins' lab began on 1st October.
Last modified: Wed, 11 Oct 2017 15:21:58 BST
EMBO Meiosis Meeting in Hvar, Croatia
Interesting talks at the EMBO Meiosis Meeting 2017, including from Owen!
Last modified: Fri, 15 Sep 2017 10:05:29 BST
Top marks and scholarship for Natalija Stepurko
Natalija, undergraduate research assistant in Owen's lab, obtained the highest Stage 2 mark in all biomedical subjects, and has spent the summer on a prestigious Amgen Scholarship at the University of Cambridge.
Last modified: Fri, 15 Sep 2017 10:25:10 BST
New paper from Josana's lab in Developmental Cell
A new paper from Josana's lab describing how aPKC cycles between functionally distinct PAR protein assemblies to drive cell polarity has just been published online in Developmental Cell
Last modified: Mon, 07 Aug 2017 11:10:10 BST
Cell Division Biology Retreat
The weather held for the Cell Division Biology Group Retreat at the Dove Marine Laboratory overlooking the beach in Cullercoats.
Last modified: Wed, 12 Jul 2017 10:24:43 BST
Outreach: "Leading Edge" project
In April, a group of pupils from St. Anthony’s Girls’ Catholic Academy led by Dr. Gillian Emery successfully conducted their “Leading Edge Project” in Jun-Yong Huang’s lab with the help of MRes student Lucy Barnsby.
Last modified: Wed, 14 Jun 2017 11:02:06 BST
Shugoshin-2 paper in Current Biology
In collaboration with Kim Nasmyth's lab, Randi Ballesteros in Mary's lab has helped explain how APC/C-Cdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes
Last modified: Thu, 31 Oct 2019 10:39:10 GMT
New paper from Jun-yong's lab
Jianquan Li, Nanmao Dang and Daniel Wood from Jun-yong's lab have a new paper published in Scientific Reports describing the kinetochore-dependent and -independent formation of the CDC20-MAD2 complex in individual cells.
Last modified: Tue, 15 Aug 2017 12:41:58 BST
Higgins and Madgwick Lab New Year Dinner
The Higgins and Madgwick labs took advantage of Newcastle's Restaurant Week and enjoyed a late New Year dinner at Blackfriars
Last modified: Mon, 27 Feb 2017 17:52:11 GMT
Randy Ballesteros defends his PhD
Randy from Mary's lab successfully defended his PhD thesis on 11th January.
Last modified: Mon, 27 Feb 2017 18:01:52 GMT
Jonny McHugh wins poster prize
Congratulations to Jonny McHugh, a Wellcome Trust summer vacation student in the labs of Alex Laude (Bioimaging Unit) and Jon Higgins, who won a Biomedical Sciences prize for his poster describing the project.
Last modified: Fri, 07 Apr 2017 10:28:34 BST
CDB Interlab Christmas Meal
CDB Interlab Meeting participants enjoyed a Christmas meal at As You Like It on December 6th.
Last modified: Fri, 16 Dec 2016 10:26:17 GMT
Outreach: Science Uncovered
The "Science Uncovered" evening at the Great North Museum included an opportunity for the public to tour the Bioimaging Unit and find out about cell division from CDB member Diana Papini.
Last modified: Mon, 07 Nov 2016 10:39:09 GMT
Bio-Imaging Outreach Event at Centre for Life
Members of the CDB Group helped out with Cell Division Day during the "Meet the Scientist" event run by Newcastle University's Bio-Imaging Unit at the International Centre for Life
Last modified: Tue, 09 Aug 2016 11:14:08 BST
Inaugural Cell Division Biology Symposium 2016
Our first Cell Division Biology Symposium was a success and there was a consensus that we should make it a recurring event.
Last modified: Wed, 27 Jul 2016 09:38:34 BST
Beccy Harris wins undergraduate prize
Congratulations to Beccy Harris who received the highest marks in Biochemistry for her undergraduate project in Jon Higgins's lab, and won the Gus Lienhard Prize for Biochemistry for the highest overall mark on her degree course.
Last modified: Fri, 15 Jul 2016 14:07:51 BST
PNT paper from the Herbert lab in Nature
A study from Mary Herbert's lab describing an improved procedure for pronuclear transfer to prevent mitochondrial disease is published in Nature.
Last modified: Thu, 09 Jun 2016 10:01:09 BST
Josana speaks at European Worm Meeting
Josana Rodriguez's talk was well-received at the recent European Worm Meeting in Berlin.
Last modified: Thu, 09 Jun 2016 14:16:42 BST
Inaugural Cell Division Biology Symposium 2016
An exciting line up of external speakers for our first Cell Division Biology Symposium on July 4th has been finalised: Iain Cheeseman, Marie-Helene Verlhac, Nate Goehring and Julie Welburn.
Last modified: Tue, 07 Jun 2016 22:23:09 BST
CDB Christmas Lunch
After the interlab meeting this week, some of the CDB group headed out for a Christmas lunch in town
Last modified: Wed, 16 Dec 2015 10:10:00 GMT
MRes Programme Prize for 2014/2015
Daniel Wood, who carried out his project in Jun-Yong Huang’s lab, has won the MRes Student Prize for 2014/2015.
Last modified: Wed, 25 Nov 2015 15:09:48 GMT
ICaMB Away Day 2015
This year's ICaMB Away Day is being held at the Tyneside Cinema. Diana Papini and Suzanne Madgwick will be speaking.
Last modified: Fri, 16 Oct 2015 14:18:17 BST
Covalent CDK inhibitor discovered
Jane Endicott's lab, in collaboration with Prof Griffin and others at the NICR, have designed and tested the first selective irreversible inhibitor of Cdk2.
Last modified: Fri, 09 Oct 2015 14:01:28 BST
MRes Poster Prize 2015
Matthew Ratcliff from Owen Davies' lab wins the prize for the best MRes poster
Last modified: Wed, 09 Sep 2015 09:54:46 BST
Undergraduate Project Prize 2015
Vincentius Aji Jatikusumo wins the ICaMB prize for his undergraduate lab project carried out in Owen Davies' lab.
Last modified: Wed, 09 Sep 2015 10:11:59 BST
EU Horizon 2020 Grant for Mary Herbert
Mary Herbert and collaborators have been awarded a major Horizon 2020 grant to study "The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem"
Last modified: Mon, 07 Sep 2015 15:10:07 BST
EMBO Conference on Meiosis 2015
Three CDB Group members will present at the upcoming EMBO Meiosis meeting in Oxford.
Last modified: Mon, 10 Aug 2015 15:02:32 BST
Diana Papini's TD-60 paper in Nature Communications
Diana's paper describing GEF activity for TD-60 in mitosis is published.
Last modified: Tue, 11 Aug 2015 13:36:55 BST
Jon Higgins becomes a Wellcome Trust Investigator
Prof Jon Higgins has been awarded a prestigious Wellcome Trust Investigator Award.
Last modified: Tue, 04 Aug 2015 16:11:02 BST
LSI - Zhejiang University visit
A delegation from the Life Sciences Institute (LSI) at Zhejiang University, China, visited in May 2015
Last modified: Wed, 15 Jul 2015 21:13:03 BST
British Meiosis Meeting in Newcastle
The British Meiosis Meeting was held in Newcastle from February 23-24th, organised by Mary Herbert, Owen Davies, Suzanne Madgwick, Raveen Sandher, Aïcha Metchat, and Mahdi Lamb.
Last modified: Mon, 27 Jul 2015 13:53:41 BST
New paper from Endicott and Noble labs
A new paper in Nature Communications from Jane Endicott's and Martin Noble's labs describes the first structure of the essential mitotic kinase Cdk1-Cyclin B, and its interaction with the regulator Cks1.
Last modified: Tue, 04 Aug 2015 16:11:05 BST
Davies Group: new publication in Nature Structural and Molecular Biology
CtIP tetramer assembly is required for DNA-end resection and repair
Last modified: Fri, 17 Jul 2015 13:31:39 BST
Owen Davies becomes a Sir Henry Dale Fellow
Congratulations to Owen Davies, who has been made a Sir Henry Dale Fellow, funded by the Royal Society and the Wellcome Trust.
Last modified: Mon, 10 Aug 2015 15:53:35 BST
Paper in eLife from Owen Davies
Owen Davies' work leads to a new model for the structure of the synaptonemal complex that holds homologous chromosomes together in meiosis.
Last modified: Tue, 04 Aug 2015 16:10:56 BST
Royal Society Wolfson Research Merit Award for Jon Higgins
Jon Higgins has received a reward to facilitate his move to Newcastle from the Brigham and Women's Hospital, Harvard Medical School.
Last modified: Tue, 04 Aug 2015 16:10:51 BST
Paper in EMBO Reports from Higgins lab
A collaborative study between the Higgins lab (Newcastle) and Fangwei Wang's lab at the LSI, Zhejiang University, China, shows how Polo-like kinase regulates Haspin in mitosis.
Last modified: Tue, 04 Aug 2015 16:10:53 BST
New Endicott and Noble paper
Different activation states of a particular Cyclin-dependent kinase may differ from each other as much as different CDKs in the same activation state.
Last modified: Mon, 27 Jul 2015 13:43:12 BST