All

All Publications

On this page, the NFRG is proud to offer you a direct access to all its publications sorted by year.

2018

  • Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2. View >
  • HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression. View >
  • NFKB1 and Cancer: Friend or Foe? View >
  • Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage. View >
  • Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2. View >
  • Reduced telomere length is associated with fibrotic joint disease suggesting that impaired telomere repair contributes to joint fibrosis. View >
  • Plasma cell-free DNA methylation: a liquid biomarker of hepatic fibrosis. View >
  • Targeting the Bacterial Cytoskeleton of the Burkholderia cepacia Complex for Antimicrobial Development: A Cautionary Tale. View >
  • Identification of a novel TIF-IA-NF-κB nucleolar stress response pathway. View >

 

2017

  • Fibroblasts Promote Inflammation and Pain via Interleukin-1α–Induction of the Monocyte Chemoattractant CCL2. View >
  • The NF-κB1 is a key regulator of acute but not chronic renal injury. View >
  • Cellular senescence drives age-dependent hepatic steatosis. View >
  • The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis. View >
  • A proof of concept for epigenetic therapy of tissue fibrosis: Inhibition of liver fibrosis progression by 3-deazaneplanocin A. View >
  • Epigenetics and Liver Fibrosis View >
  • The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion. View >
  • Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion. View >
  • Variant Histone H2afv reprograms DNA methylation during early zebrafish development. View >

 

2016

  • Plasma DNA Methylation: A Potential Biomarker for Prognostic Stratification of Liver Fibrosis in Non-Alcoholic Fatty Liver Disease View >
  • A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo. View
  • TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury. View >
  • A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer. View >
  • Mitochondria are required for pro-ageing features of the senescent phenotype. View >
  • Liver: Osteopontin and HMGB1: novel regulators of HSC activation. View >
  • Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFa stimulation regulates DNA binding and transcription. View >
  • Epigenetics in liver disease: from biology to therapeutics. View >
  • International consensus on the definition and classification of fibrosis of the knee joint. View >
  • The Role of the Fibroblast in Inflammatory Upper Airway Conditions. View >
  • Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape. View >
  • Pseudomonas aeruginosa induced airway epithelial injury drives fibroblast activation: a mechanism in chronic lung allograft dysfunction View >
  • The role of exosomes in the pathogenesis of Pancreatic Ductal Adenocarcinoma". The International Journal of Biochemistry & Cell Biology. View >
  • DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease View >
  • Response to 'Comment on 'The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome''. View >
  • Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2. View >
  • Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum. View >
  • Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease. View >
  •  Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis View >
  • Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis. View >
  • Acidic chitinase primes the protective immune response to gastrointestinal nematodes. View >
  • The IL-1 cytokine family and its role in inflammation and fibrosis in the lung. View >
  • Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A. View >

 

2015

  • NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. View >
  • Alcohol directly stimulates epigenetic modifications in hepatic stellate cells. View >
  • Emerging and disease-specific mechanisms of hepatic stellate cell activation. View >
  • Epigenetic regulation of liver fibrosis. View >
  • How reliable are sino-nasal cell lines for studying the pathophysiology of chronic rhinosinusitis? View >
  • Joint Stiffness Is Heritable and Associated with Fibrotic Conditions and Joint Replacement. View >
  • Novel therapeutic targets in primary biliary cirrhosis. View >
  • Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease. View >
  • Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the health and environmental sciences institute. View >
  • A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty. View >
  • Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells. View >
  • The role of pancreatic stellate cells in pancreatic cancer View >
  • Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease. View >
  • Gain-of-function STAT1 mutations impair STAT3 activity in patients with Chronic Mucocutaneous Candidiasis (CMC) View >
  • Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation. View >
  • Transfusion reactions in pediatric compared with adult patients: a look at rate, reaction type, and associated products. View >
  • An expandable donor-free supply of functional hepatocytes for toxicology. View >
  • Fibrosis is a common outcome following total knee arthroplasty. View >
  • TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma. View >
  • NFKB1: a Suppressor of Inflammation, Ageing, and Cancer. View >

 

2014

  • A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. View
  • Epigenetics in liver disease. View
  • How reliable are sino-nasal cell lines for studying the pathophysiology of chronic rhinosinusitis? View
  • Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3. View >
  • A reversible model for periportal fibrosis and a refined alternative to bile duct ligation View
  • IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. View >
  • Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. View >
  • Arrested development and the great escape--the role of cellular senescence in pancreatic cancer. View >
  • Transfusion reactions in pediatric compared with adult patients: a look at rate, reaction type, and associated products. View >
  • Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB. View >
  • Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker. View >
  • Utility of B-13 progenitor-derived hepatocytes in hepatotoxicity and genotoxicity studies. View >
  • Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis. View >
  • TNF-α/IL-17 synergy inhibits IL-13 bioactivity via IL-13Rα2 induction. View >
  • Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation. View >
  • Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation. View >

 

2013

  •  Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells View >
  • Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. View >
  • Serotonin paracrine signaling in tissue fibrosis. View >
  • The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice. View >
  • Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model. View >
  • TNFα from classically activated macrophages accentuates epitheial to mesenchymal transition in obliterative bronchiolitis. View >
  • Epigenetic regulation of wound healing and fibrosis. View >
  • An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury. View >
  • Epigenetic modifications as new targets for liver disease therapies. View >
  • The potential contribution of tumor-related factors to the development of FOLFOX induced sinusoidal obstruction syndrome. View >
  • Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter. View >
  • Epigenetic regulation of wound healing and fibrosis. View >
  • A reversible model for periportal fibrosis and a refined alternative to bile duct ligation. View >
  • Transfusion reactions in pediatric compared with adult patients: a look at rate, reaction type, and associated products. View >
  • A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. View >
  • Utility of B-13 progenitor-derived hepatocytes in hepatotoxicity and genotoxicity studies. View >
  • The impact of tumor size in breast needle biopsy material on final pathologic size and tumor stage: a detailed analysis of 222 consecutive cases. View >
  • Role of arginase 1 from myeloid cells in th2-dominated lung inflammation. View >
  • Cytokine-mediated tissue fibrosis. View >
  • Multigenerational epigenetic adaptation of the hepatic wound-healing response. View >

 

2012

  • The Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation View >
  • Multigenerational Epigenetic Adaptation of the Hepatic Wound-Healing Response View >
  • Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL. View >
  • The NF-κB subunit c-Rel stimulates cardiac hypertrophy and fibrosis. View >
  • Clinical evidence for the regression of liver fibrosis. View >
  • Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans. View >
  • Seamless replacement of Autographa californica multiple nucleopolyhedrovirus gp64 with each of five novel Type II Alpha-baculoviral F sequences generates pseudotyped virus that fails to transduce mammalian cells. View >
  • The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation. View >
  • The tumor necrosis factor receptor stalk regions define responsiveness to soluble versus membrane-bound ligand. View >
  • Transforming growth factor-β1 driven epithelial to mesenchymal transition (EMT) is accentuated by tumor necrosis factor α via crosstalk between the SMAD and NF-κB pathways. View >
  • Rosmarinic acid and baicalin epigenetically de-repress Pparγ in hepatic stellate cells for their anti-fibrotic effect. View >
  • Telomeres are favored targets of a persistent DNA damage response in ageing and stress-induced senescence. View >
  • Serotonin paracrine signaling in tissue fibrosis. View >
  • Roles of c-Rel signalling in inflammation and disease. View >
  • BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis. View >
  • Mechanisms and biomarkers of apoptosis in liver disease and fibrosis. View >
  • Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism. View >
  • Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells View >

 

2011

  • Stimulating healthy tissue regeneration by targeting the 5-HT(2B) receptor in chronic liver disease. View >
  • Human T-cell leukemia virus type 1 Tax transactivates the matrix metalloproteinase 7 gene via JunD/AP-1 signaling. View >
  • Epigenetic cell fate regulation of hepatic stellate cells. View >
  • Transfusion reactions in pediatric compared with adult patients: a look at rate, reaction type, and associated products. View >
  • BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis. View >
  • The NF-κB subunit c-Rel stimulates cardiac hypertrophy and fibrosis. View >
  • Is CFTR-delF508 really absent from the apical membrane of the airway epithelium? View >
  • Transforming Growth Factor-β1 (TGF-β1) Driven Epithelial to Mesenchymal Transition (EMT) is Accentuated by Tumour Necrosis Factor α (TNFα) via Crosstalk Between the SMAD and NF-κB Pathways. View >
  • Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation. View >
  • Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL. View >

 

2010

  • MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis. View >
  • The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple proinflammatory genes. View >
  • The c-Rel subunit of NF-kB regulates murine liver inflammation, wound-healing and regeneration. View >
  • The PXR is a drug target for chronic inflammatory disease. View >
  • A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells. View >
  • Fibrogenic signaling in hepatic stellate cells. View >
  • Allele-specific regulation of matrix metalloproteinase-3 gene by transcription factor NF-κB. View >
  • Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF-kB signalling pathways. View >
  • Role of nuclear factor kappa B in liver health and disease. View >
  • NF-kappaB signalling: Embracing complexity to achieve translation. View >
  • Counter-selection recombineering of the baculovirus genome: a strategy for seamless modification of repeat-containing BACs View >
  • Opposing putative roles for canonical and noncanonical NF-kB signaling on the survival, proliferation, and differentiation potential of human embryonic stem cells. View >
  • The c-Rel subunit of nuclear factor-kappaB regulates murine liver inflammation, wound-healing, and hepatocyte proliferation. View >
  • Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis. View >
  • Regulation of NF-κB responses by epigenetic suppression of IκBα expression in HCT116 intestinal epithelial cells View >
  • Epigenetic downregulation of human Disabled-2 switches TGF-beta from a tumor suppressor to a tumor promoter. View >
  • Low strength T-cell activation promotes Th17 responses. View >
  • Lung epithelial wound healing in health and disease. View >
  • Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway. View >
  • Inflammation and epithelial to mesenchymal transition in lung transplant recipients: role in dysregulated epithelial wound repair. View >

 

2009

  • Angiotensin II activates IκB kinase phosphorylation of RelA at Ser536 to promote myofibroblast survival and liver fibrosis. View >
  • Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue. View >
  • Active matrix metalloproteinase-2 promotes apoptosis of hepatic stellate cells via the cleavage of cellular N-cadherin. View >
  • Systemic chemotherapy and its implications for resection of colorectal liver metastasis. View >
  • Transcriptional regulation of hepatic stellate cells. View >
  • Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane. View >
  • Differences in activities of daily living performance between long-term pediatric sarcoma survivors and a matched comparison group on standardized testing. View >
  • Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha. View >
  • Signaling components of redox active endosomes: the redoxosomes. View >
  • Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation. View >

 

2008

  • Hepatic NF-kB regulates neutrophil recruitment to the injured brain. View >
  • NF-kB is a critical regulator of the survival of rodent and human hepatic myofibroblasts View >
  • Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic livers. View >
  • The function of serotonin within the liver. View >
  • Wound healing and local neuroendocrine regulation in the injured liver. View >
  • Epigenetic regulation of liver fibrosis. View >
  • A mechanism for the antifibrogenic effects of the pregnane X receptor (PXR) in the liver: Inhibition of NF-B. View >
  • Fibrosis and cirrhosis reversibility - molecular mechanisms. View >
  • ZAP70 in chronic lymphocytic leukaemia. View >
  • Epigenetic regulation of hepatic stellate cell activation. View >
  • Multidrug resistance-associated proteins are crucial for the viability of activated rat hepatic stellate cells. View >
  • Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis. View >
  • Occupational therapists' role on U.S. Army and U.S. Public Health Service Commissioned Corps Disaster Mental Health Response Teams. View >
  • JunD protects the liver from ischemia/reperfusion injury by dampening AP-1 transcriptional activation. View >
  • Nuclear factor-kappaB1: regulation and function. View >
  • Defective formation of PKA/CnA-dependent annexin 2-S100A10/CFTR complex in DeltaF508 cystic fibrosis cells. View >
  • The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia. View >
  • Airway epithelial cell senescence in the lung allograft. View >
  • CMT3 alters mitochondrial function in murine osteoclast lineage cells View >

 

2007

  • Nuclear Factor-KappaB and the hepatic inflammation-fibrosis-cancer axis. View >
  • Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis. View >
  • Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells. View
  • Nuclear factor-kappaB1: regulation and function. View >
  • Cross-cultural reproducibility of the Brazilian Portuguese version of the Role Checklist for persons with chronic obstructive pulmonary disease. View >
  • The formation of the cAMP/protein kinase A-dependent annexin 2-S100A10 complex with cystic fibrosis conductance regulator protein (CFTR) regulates CFTR channel function. View >

 

Before 2007

  • (2006). Resolving fibrosis in the diseased liver: translating the scientific promise to the clinic View >
  • (2006) JunD is a profibrogenic transcription factor regulated by Jun-N-terminal Kinase (JNK)-independent phosphorylation. View >
  • (2006) Pharmacological inhibitors of NF-kB accelerate apoptosis in chronic lymphocytic leukaemia cells. View >
  • (2006) A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. View >
  • (2006) Pregnane X receptor activators inhibit human hepatic stellate cell transdifferentiation in vitro. View >
  • (2006) Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats. View >
  • (2005) Functional Analysis of HIV Type 1 Nef Reveals a Role for PAK2 as a Regulator of Cell Phenotype and Function in the Murine Dendritic Cell Line View >
  • (2005) Regulation of hepatic stellate cell apoptosis and recovery from liver fibrosis. View >
  • (2005) NF-kB: A signal for cancer. View >
  • (2005) RNA interference mediated in human primary cells via recombinant baculoviral vectors. View >
  • (2005) Herpesvirus saimiri-based vector biodistribution using non-invasive optical imaging. View >
  • (2005) Novel sulfasalazine analogues with enhanced NF-B inhibitory and apoptosis promoting activity. View >
  • (2005) NFkB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury. View >
  • (2005) Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. View >
  • (2004). N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1. View >
  • (2004) Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2. View >
  • (2004) MMP-9 gene transcription is induced in myofibroblasts cultured in 3-D collagen I gels: regulation by NF-kB, AP1 and Sp1. View >
  • (2004) A failure of transforming growth factor-beta1 negative regulation maintains sustained NF-kappaB activation in gut inflammation. View >
  • (2004) Signal transduction via the NF-B pathway: A targeted treatment modality for infection, inflammation and repair. View >
  • (2003) Hepatocytes express nerve growth factor during liver injury: Evidence for paracrine regulation of hepatic stellate cell apoptosis. View >
  • (2003) Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP-J (CBF1) and its activator Notch1. View >
  • (2003) Characterisation of the murine Natural resistance-associated protein 1 promoter: requirements for trans-activation by Miz-1. View >
  • The NF-kB luciferase mouse: a new tool for real time measurement of NF-kB activation in the whole animal. View >
  • (2002) c-Myc represses and Miz-1 activates the murine natural resistance-associated protein 1 promoter. View >
  • (2002) CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-kappa B, AND CBF1. View >
  • (2002) High-efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors. View >
  • (2001) Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. View >
  • (2002) Transcriptional regulation of hepatic stellate cell activation. View >
  • (2001). JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells. View >
  • (2001) Regulation of E-box DNA binding activities during in vivo and in vitro activation of rat and human hepatic stellate cells. View >
  • (2000) Attenuation and augmentation of ischaemia-related neuronal death by tumour necrosis factor-alpha in vitro. View >
  • (2000) Chromosomes and Cirrhosis: All's well that ends well. View >
  • (2000) Upstream TIMP-1 element-1 (UTE-1) is a novel and essential regulatory DNA motif in the human TIMP-1 gene promoter that directly interacts with a 30kDa nuclear protein. View >
  • (2000) CTL epitopes of HIV-1 Nef: Generation of multiple definitive MHC class I ligands by proteasomes. View >
  • (1999) Identification of the Nef-associated kinase as p21-activated kinase 2. View >
  • (1999) A macrophage hippocampal slice co-culture system: application to the study of HIV induced brain damage. View >
  • (1999) Persistent activation of nuclear factor-kappaB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkappaB family proteins. View >
  • (1999) A bi-functional activator/repressor element required for transcriptional activity of the human UCH-L1 gene assembles a neuron-specific protein: single-strand DNA complex. View >
  • (1999) A soluble factor produced by macrophages mediates the neurotoxic effects of HIV-1 Tat in vitro. View >
  • (1999) Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 Nef is a cell type specific response that requires both Hck and MAPK signaling events. View >
  • (1999) Tissue inhibitors of metalloproteinases: role in liver fibrosis and alcoholic liver disease. View >
  • (1999) Control of the tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter in culture activated rat hepatic stellate cells: Regulation by AP-1 DNA binding proteins. View >
  • (1998) The pathogenesis of liver fibrosis: A role for altered matrix degradation. View >
  • (1998) Tissue inhibitors of metalloproteinases, hepatic stellate cells and liver fibrosis. View >
  • (1998) A proposed mechanism for the induction of Activator Protein 1 (AP-1) binding by HIV-1 Negative Factor (Nef) in the macrophage cell line RAW267.4. View >
  •  (1997) Transcriptional activity of the human tissue inhibitor of metalloproteinases 1 (TIMP-1) gene in fibroblasts involves elements in the promoter, exon 1 and intron 1. View >
  • (1997) Protein kinase C-mediated phosphorylation of HIV-1 Nef in human cell lines. View >
  • (1997) Analysis of the interactions between Nef and cellular proteins. View >
  • (1997) Regulated expression vectors demonstrate cell-type-specific sensitivity to human immunodeficiency virus type-1 Nef-induced cytostasis. View >
  • (1996) The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line. View >
  • (1996) Detection of neuron-specific protein gene product (PGP) 9.5 in the rat and zebrafish using anti-human PGP9.5 antibodies. View >
  •  (1996) Identification of evolutionary conserved regulatory sequences in the 5' untranscribed region of the neural-specific ubiquitin C-terminal hydrolase (PGP9.5) gene. View >
  • (1994) A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression. View >
  • (1993) HIV regulatory proteins Tat and Rev and their interactions with synthetic RNA. View >
  • (1992) Recognition of the high affinity binding site in Rev-response element RNA by the human immunodeficinecy virus type-1 Rev protein. View >
  • (1992) Alternative splicing of the cytoplasmic domain of the neural cell adhesion molecule alters its ability to act as a substrate for neurite outgrowth. View >
  • (1991) Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs. View >
  • (1990) Characterisation of the human NCAM gene promoter. View >
  •  (1990) Characterization of a regulatory region within the human neural cell adhesion molecule gene. View >
  •  (1989) Increased intracellular cyclic AMP differentially modulates nerve growth factor induction of three neuronal recognition molecules involved in neurite outgrowth. View >
  •  (1988) Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures. View >
  •  (1987) Cholera toxin and dibutyryl cyclic AMP inhibit the expression of neurofilament protein induced by nerve growth factor in cultures of naive and primed PC12 cells. View >
  • (1987) Cell-cell interactions modulate the responsiveness of PC12 cells to nerve growth factor. View >
  • Functional analysis of Human Immunodeficiency Virus Type 1 Nef reveals a role for PAK2 as a regulator of cell phenotype and function in the murine dendritic cell line, DC2.4 View >
  • Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis.d View >
  • The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. View >
  • Comparative EST analyses in plant systems. View >