Prof. Jelena Mann, a Principal Investigator within NFRG, has recently brought her contribution to an article, freshly published in Gastroenterology, entitiled:

INTEGRATED MULTI-OMICS REVEALS GLUCOSE USE REPROGRAMMING AND IDENTIFIES A NOVEL HEXOKINASE IN ALCOHOLIC HEPATITIS

Previous research demonstrated that alcoholic hepatitis (AH) is characterized by de-differentiation of hepatocytes and loss of mature functions. Glucose metabolism is tightly regulated in healthy hepatocytes. In consequence, the authors hypothesized that AH may lead to metabolic reprogramming of the liver, including dysregulation of glucose metabolism..

Click HERE to read the press release on the website of University of Manchester