From January 20-24, Prof. Jelena Mann has been representing Newcastle Fibrosis Research Group in Santa Fe at Keystone Symposia on Integrated Pathways of Diseases in NASH and NAFLD where she was invited as a guest speaker.

During the Fibrosis and Cancer - Mechanisms and Markers session held on Wednesday the 23rd of January, Professor Mann gave her talk entitled:

Epigenetics of Fibrosis and Cancer in Liver Disease.

The goal of this meeting, as described by the organisers was:

1) Explore genetic and ethnic contributions to NAFLD development;

2) Clarify underlying pathogenic defects in NAFLD and NASH, focusing on the specific contributions of lipotoxicity, the microbiome, innate immune signalling, and drivers of fibrosis;

3) Highlight emerging prognostic and diagnostic biomarkers that are yielding new, more streamlined clinical trial designs that evaluate novel therapies.

Click HERE for more details and to view the full program