Dr. Ian Hardcastle

• Reader in Medicinal Chemistry
• Email: ian.hardcastle@ncl.ac.uk
• Telephone: +44 (0) 191 208 6645

Ian Hardcastle is a Reader in Medicinal Chemistry. He started at Newcastle as Lecturer in 1999, moving from a postdoctoral fellowship within the DDU at the Institute of Cancer Research (1990-1999). At the ICR he was a member of the team that discovered Zytiga (abiraterone acetate). He has extensive experience of hit-to-lead chemistry and a particular interest in protein-protein interaction inhibitors, having led the Newcastle lead optimisation medicinal chemistry for the recent MDM2-p53 inhibitor project. University profile.