Introduction to 1958 Birth Cohort
The 1958 National Child Development Study (NCDS) is following the lives of an initial 17,415 people born in England, Scotland and Wales in a single week of 1958. The data from this study is made available to research scientists from anywhere in the world that have successfully applied via the relevant Data Access Committee. The study is based at the Centre for Longitudinal Studies at UCL - https://cls.ucl.ac.uk/cls-studies/1958-national-child-development-study/
The resource is used widely for:
- research in genetic and genomic epidemiology, in particular as a platform for genetic association studies.
- providing a source of subjects that have been well characterised (phenotyped) for a variety of quantitative complex traits and have also been assessed for a variety of socio-demographic, socio-economic and life style variables that are outcomes in their own right, and may be important determinants in relevant causal pathways leading to disease
- providing a source of ‘cases’ and ‘controls’ for common binary traits
- providing a geographically representative sample of British people (of primarily European origin) that represents the premier source of national controls that can be used in a wide variety of genetic case-control studies
Restrictions for the commercial use of the 1958 BC resource are currently in place.