Millenium Cohort Genetics

Genetic Data Types

Genetics data available from the Millennium Cohort Study is managed on behalf of the Centre for Longitudinal Studies [https://cls.ucl.ac.uk/] at UCL, and is listed below. For details on how to access see CLS Data Access [https://cls.ucl.ac.uk/data-access-training/data-access/]

The sampling, DNA extaction and genotyping process is detailed in the CLS working paper [https://cls.ucl.ac.uk/wp-content/uploads/2020/08/CLS-working-paper-2020-7-Collection-of-DNA-samples-and-genetic-data-at-scale-in-the-UK-Millennium-Cohort-Study.pdf]

Datasets available:

  - Genotype data (Infinium GSA-24 v1.0) (21230 samples; 618540 SNPs)

  - Imputed data (HRC 1.1) (21230 samples)

  - Illumina GenomeStudio Final Report (21230 samples)

Illumina GenomeStudio Final Report

Final report for all 21230 genotyped samples in text format from Illumina GenomeStudio v2.0, including GC Score, B Allele Freq and Log R Ratio.

Genotype data

Data for 21230 samples genotyped using Illumina Infinium global screening arrays-24 v1.0, with 618540 SNPs.

Imputed data

Data for 21230 samples imputed to Haplotype Reference Consortium release 1.1 (HRC r1.1; http://www.haplotype-reference-consortium.org). See the CLS working paper for further details (CLS working paper [https://cls.ucl.ac.uk/wp-content/uploads/2020/08/CLS-working-paper-2020-7-Collection-of-DNA-samples-and-genetic-data-at-scale-in-the-UK-Millennium-Cohort-Study.pdf]).