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We aim to gain a new understanding of the rules that determine the growth and dynamics of complex biological communities in engineered applications. This will also account for hydrodynamic and biomechanical properties.

The research uses a variety of techniques that will be developed and adapted for this programme. We expect to use new applications and analytical methods, such as a new generation of scalable models that take account of biology, chemistry, physical and hydrodynamic behaviours.

It may also lead to new theoretical insights that we haven't yet imagined, as we watch the emergent behaviour of the systems.

We expect to gain new insights into:

  • the ecology of microorganisms
  • the robustness and application of synthetic biological techniques and the organisms it produces
  • the coupled behaviour of complex communities and their physical and chemical environment
  • how these complex behaviours manifest themselves into engineered functions.

The project will be run in three overlapping phases:

Phase 1

Phase 1

Create the pieces needed to progress the research. We'll use tools to predict how microbes grow, flow and change in systems.

Phase 2

Phase 2

Combine the pieces to validate the ideas and see how it applies to other models.

Phase 3

Phase 3

Further refine the work or address any problems that have come up throughout the research.

NUFEB Individual-based Model

NUFEB Individual-based Model for multi-species bacterial attachment, biofilm formation, flow-induced deformation and detachment

To try the model out for yourself click