Rhianna Baldwin

• CDT Doctoral Researcher Supervisor: Prof Wyatt Yue
• Email: r.baldwin2@newcastle.ac.uk
• Project Title: A novel drug discovery workflow combining DNA-encoded library, AI machine learning and cryo-electron microscopy.

Institution: Newcastle University

Project Summary: I am using a novel drug discovery workflow to identify small molecule compound hits for a metabolic enzyme, which has been implicated as a therapeutic target for rare genetic diseases, underpinned by inborn errors of metabolism. This approach aims to facilitate structure based drug discovery for targets recalcitrant to crystallography.

Interesting Fact: Prior to starting my degree, I worked as a technician in the watchmaking industry.