2010

Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia. Schwab CJ et al Gene Chromosomes Cancer 2010 49(12):1104-13

Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group. Harrison CJ et al Br. J. Haematol 2010 151(2):132-42

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Grimwade D et al Blood. 2010 116(3):354-65.

A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia. Chapiro E et al Leukemia. 2010 24:1362-64.

Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Sherborne AL et al Nature Genetics. 2010 June;42(6):492-94.

Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12. Harrison CJ et al J Clin Oncol. 2010 June;28(16):2674-81.

Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. Moorman AV et al Lancet Oncol. 2010 May;11(5):429-438.

PHF6 mutations in T-cell acute lymphoblastic leukemia. Van Vlierberghe P et al Nature Genetics. 2010 Apr;42(4):338-342.

Haploinsufficiency of the MLL and TOB2 genes in lymphoid malignancy. An Q et al Leukemia. 2010 Mar; 24(3):649-52.

Cytogenetics of long-term survivors of ETV6-RUNX1 fusion positive acute lymphoblastic leukemia. Konn ZJ et al Genes Chromosomes Cancer. 2010 Mar;49(3):253-9.

Antigen receptor gene rearrangements reflect on the heterogeneity of adult Acute Lymphoblastic Leukaemia (ALL) with implications of cell-origin of ALL subgroups - a UKALLXII study. Rai L et al Br J Haematol. 2010 Feb; 148(3):394-401.

Temporal changes in the incidence and pattern of central nervous system relapses in children with acute lymphoblastic leukaemia treated on four consecutive Medical Research Council trials, 1985-2001. Krishnan S et al Leukemia. 2010 Feb; 24(2):450-59.

Long-term follow-up of the United Kingdom medical research council protocols for childhood acute lymphoblastic leukaemia, 1980-2001. Mitchell C et al Leukemia. 2010 Feb; 24(2):406-18.

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. Hertzberg L et al Blood. 2010 Feb 4;115(5):1006-17.

A population-based cytogenetic study of adults with acute lymphoblastic leukemia. Moorman AV et al Blood. 2010 Jan 14;115(2):206-14.

Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993. Patel B et al Br J Haematol. 2010 Jan; 148(1):80-89.

Genetic aberrations in paediatric acute leukaemias and implications for management of patients. Szczepanski T et al Lancet Oncol. 2010 Sep;11(9):880-889.