Name

Surname

Research area and interests

To share

Shoba

Amarnath

cancer immunology, fundamental immunology, preclinical models, aging immune system

Aged mouse models of cancer, autoimmunity and GvHD once license is approved, flow cytometry, single cell analysis protocols, spatial transcriptomics, immunephenotyping panels

Michael

Carroll

Synthesis of bioactive compounds, QC standards etc for various applications

Alessandra

Da Silva Dantas

microbiology, redox signaling, host-pathogen interactions (with a focus on the pathogen), antifungal resistance and infection biology

Joanna

Elson

Andrew

Filby

Antoneta

Granic

epidemiology of ageing, mechanisms of skeletal muscle ageing and sarcopenia, mutimorbidity (MLTC), nutritional epidemiology and muscle ageing.

Kate

Harris

Chemical biology

Andrew

Kingston

Viktor

Korolchuk

autophagy, cell senescence, mitochondrial function, cell metabolism, cell models of neurodegenerative disease, drug discovery

cell lines, plasmids, genome editing, lentiviral delivery of constructs into cells

Jack

Leslie

Cell senescence, SASP, cell metabolism, immunology in ageing and cancer, preclinical models, therapeutic interventions

Chronic liver disease and cancer mouse model tissues, flow cytometry, multiplexed imaging

John

Loughlin

Saimir

Luli

in vivo imaging

Derek

Mann

Liver senescence in disease and cancer, pre-clinical models including mouse and human with in vivo and in vitro capabilities.

Mouse and human models including precision cut tissue slices

Carmen

Martin-Ruiz

Cell senescence, Biomarkers of Ageing, Translational Studies, Inflammation and Immunosenescence

BioScreening core Facility, Clinical Trials GCP Regulatory Services.

Satomi

Miwa

cell senescence, mitochondrial function, cell metabolism, Seahorse methods, pre-clinical mouse studies, senolytics, drug discovery, sex differences

ageing mice tissue bank, Seahorse analyzer and Oroboros methods, cell senescence assessments, ageing phenotyping in mice, home office project license (ageing mice)

Glyn

Nelson

Microscopy, image analysis, molecular biology techniques

Fiona

Oakley

Katarzyna

Pirog

cartilage development and disease, chondrodysplasias, osteoarthritis and healthy skeletal ageing, ER and oxidative stress, tissue engineering, mechanosensing

hydrogel models of cartilage, Flexcell dynamic compression system, mechanical testing of bones and tendons, phenotyping of animal models of skeletal disease, Faxitron VersaVision high resolution Xray imager, home office project licence

Louise

Reynard

Sarah

Rice

Gavin

Richardson

Karen

Suetterlin

channelopathy, rare neuromuscular disease, ageing, neurophysiology, pre-clinical & clinical studies

Simon

Tual-Chalot

endothelial  cell, pre-clinical mouse studies, RNA metabolism

tissue from aged mice, Ibidi flow chamber (put endothelial cell in context of mechanic stress similar to blood), hypoxia chamber, aged mice project licence

Elizabeth

Veal

Redox Signaling, Stress responses, Mitochondrial function

C. elegans and yeast chronological aging. High throughput genetic screening in C. elegans (RNAi) and fission yeast S. pombe (mutant library). Redox regulation of proteins. MAPK signaling.

Amy

Vincent

Thomas

von Zglinicki

cell senescence, anti- ageing interventions, biomarker for human and mouse ageing studies

multinational networks in ageing biology

Stephen

White

Endothelial Biology, smoking (accelerated senescence), Antioxidant control (Nrf2), Senescence & autophagy, Epigenetics (grants in for epigenetics and outcomes in diabetes = accelerated aging).

endothelial ‘omics, smoking models, transcription factor reporters, lenti vector cell immortalization (hTert/BMI1), potentially epigenetics and genotyping in diabetic cohorts if grants are funded

David

Young