Objectives
DNASURF aims to transform creative scientific ideas into innovative biomedical products for DNA diagnostics by exploiting and integrating advances in DNA synthesis, nanotechnology, interfacial engineering, and microsystems research. Specific objectives are:
- To develop and expand enzymatic and chemical methods for synthesis of site-specifically modified DNA to produce designer sequences with selective functional properties
- To use DNA as a scaffold or template for assembly of functional materials with a view to introducing novel conductive, photonic, recognition, and supramolecular properties
- To characterise the behaviour of native and modified DNA at functional surfaces in relation to interfacial interactions, chemical bridges, organisation, dynamics, and detection modalities
- To integrate native and modified DNA molecules with functional materials to create miniaturized and microfluidic devices for application in point-of-care medical diagnostics
- To enhance high level technical, theoretical, and experimental skills of seconded researchers through hands-on training and "learning-by-doing" during secondments
- To strengthen ongoing scientific collaborations between European and International partners