Previous Seminars
NICR Seminar - Prof Stefan Knapp
- Venue: Paul O'Gorman Building Seminar Room
- Start: Mon, 04 Dec 2017 13:00:00 GMT
- End: Mon, 04 Dec 2017 14:00:00 GMT
Professor Stefan Knapp, Goethe-University Frankfurt Institute for Pharmaceutical Chemistry, Germany
Title: Selective targeting of kinase catalytic and non-catalytic function.
Prof Knapp's talk will summarise strategies that led to the development of highly selective inhibitors. He will also discuss the discovery of novel inhibitor binding sites including allosteric sites and the exploitation of unusual structural features for the design of highly selective kinase inhibitors, as well as structural aspects optimizing inhibitor residence times.