Programme
10:00 Welcome
10:05 Marie-Hélène Verlhac, Collège de France; Why centre the nucleus in mouse oocytes?
10:40 Nate Goehring, Francis Crick Institute; Design principles of the PAR polarity network
11:15 Josana Rodriguez Sanchez; Dynamic balance of aPKC activity between distinct complexes is required for polarization of the C. elegans zygote
11:35 Break – Tea/coffee in David Shaw LT Foyer
12:00 Suzanne Madgwick; Two-step Cyclin B1 destruction prevents segregation errors in oocytes
12:20 James Dunce; The molecular basis of meiotic chromosome synapsis by SYCP1
12:40 Randy Ballesteros Mejia; Female reproductive ageing: when during oogenesis do chromosomes begin to fall apart?
13:00 Lunch. For speakers: sandwich lunch provided. For participants: please find lunch yourself
14:00 Iain Cheeseman, Whitehead Institute/MIT; Building the centromere-kinetochore interface
14:35 Julie Welburn, University of Edinburgh; Molecular mechanism of mitotic motors
15:20 Stephen Hallett; Differential regulation of G1 CDK complexes by the HSP90-CDC37 chaperone system
15:40 Break – Tea/coffee in David Shaw LT Foyer
16:00 Joana Rodrigues; PAF1 complex components regulate TERRA and telomere function
16:20 Paul Jowsey; Identification of Microcephalin-1 as a novel target of the Anaphase Promoting Complex
16:40 Jane Endicott; CDK-cyclin complexes: conserved and unique sites for protein binding
17:00 Nanmao Dang; Kinetochore-dependent and independent formation of the CDC20-MAD2 complex and its functions in HeLa cells
17:20 Jonathan Higgins; Adventures in histone phosphorylation
17:40 Concluding remarks
18:00 Dinner, Mezzanine Room, McKenna’s at Northern Stage. For registered participants only, please