Previous Seminars
ICaMB seminar - Prof Iain Hagan
- Venue: Baddiley-Clark Seminar Room
- Start: Wed, 20 Apr 2016 13:00:00 BST
- End: Wed, 20 Apr 2016 14:00:00 BST
Prof Hagan will give the ICaMB seminar, “A protein phosphatase 1/protein phosphatase 2A rely controls mitotic progression”, hosted by David Lydall.
After completing his PhD studies with Jerry Hyams and Paul Nurse in London, Iain went to Japan for a postdoctoral fellowship with Professor Mitsuhiro Yanagida at Kyoto University. He returned to the UK in 1993 to establish a group at The University of Manchester. He continued to work in what later became the Faculty of Life Sciences at The University of Manchester, with Cancer Research Campaign Fellowship support, before moving to the Paterson Institute for Cancer Research in 2001. He was awarded the Human Frontier Science Program 10th Anniversary Medal (1999), is a recipient of the BSCB Hooke Medal (2001), and was elected member of EMBO (2009). Iain is currently a Senior Group Leader at Cancer Research UK Manchester Institute.
Recent Publications:
Grallert A, Boke E, Hagting A, Hodgson B, Connolly Y, Griffiths JR, Smith DL, Pines J, Hagan IM. A PP1-PP2A phosphatase relay controls mitotic progression. Nature 517:94-98 (2015)
Tay YD, Patel A, Kaemena DF, Hagan IM. Mutation of a conserved residue enhances sensitivity of analogue sensitized kinases to generate a novel approach for mitotic studies in fission yeast. Journal of Cell Science 126: 5052-5061 (2013)
Grallert A, Chan KY, Alonso-Nuñez ML, Madrid M, Biswas A, Alvarez-Tabarés I, Connolly Y, Tanaka K, Robertson A, Ortiz J-M, Smith DL, Hagan IM. Removal of centrosomal PP1 by NIMA Kinase unlocks the MPF feedback loop to promote mitotic commitment in S. pombe. Current Biology 23:213-222 (2013)
Grallert A, Patel A, Tallada VA, Chan KY, Bagley S, Krapp A, Simanis V, Hagan IM. Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast. Nature Cell Biology 15:88-95 (2013)
Sponsored by: Eurogentec