Previous Seminars
High-Content Imaging Mini Symposium
- Venue: Leech Building L2.6
- Start: Tue, 07 Mar 2017 14:00:00 GMT
- End: Tue, 07 Mar 2017 16:30:00 GMT
During this session, speakers will present their experiences of high-content imaging and the various assays they use within their facilities.
You will hear about our current capabilities in this area but there is a strong possibility of investment in this technology in the near future so this symposium will be a great way to learn more and see if high-content imaging can help increase the throughput of your research. For those of you who are unfamiliar with the term high-content imaging / analysis:
"High-content imaging / analysis (HCA) is a method that is used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in a desired manner. Phenotypic changes may include increases or decreases in the production of cellular products such as proteins and/or changes in the morphology (visual appearance) of the cell. High content analysis includes any method used to analyse whole cells or components of cells with simultaneous readout of several parameters.
In high content imaging, cells are first incubated with the substance (live-cell label, antibody-based label or other method of fluorescent dye delivery) and once labelled, structures and molecular components of the cells are imaged. Through the use of differently coloured fluorescent tags, it is possible to measure several different cellular components simultaneously. Imaging is able to detect changes at a subcellular level (e.g., cytoplasm vs. nucleus vs. other organelles). The technique allows population data to be collected at a sub-cellular level."
Programme
14:00 Introduction and overview of our current capabilities - Alex Laude / Oliver Russell
14:15 FMS screening and robotics facility - Peter Banks
14:30 What is high-content imaging? - Jacob Tesdorpf (PerkinElmer)
COFFEE BREAK
15:15 Investigating cell division using high-content imaging – Nik Watson (Higgins group)
15:30 An academic high-content imaging facility - Steve Bagley (Patterson Institute Manchester)
16:00 High-content imaging in pharma - Stephen Helliwell (Novartis, Switzerland)
This will be a very informative session and we hope that you can attend.
To register your interest in the event and to tell us more about your current and future image-based screening plans please complete the online form: