Objectives

 - To develop aids to diagnosis for non-specialist doctors, such as questionnaires appropriate for LMIC settings, and equipment that measures slowness of movement and tremor, the two major symptoms of PD. 

 - To provide training for doctors, nurses and therapists to improve diagnosis and management. 

 - To develop and trial services for diagnosis and management of PD by non-specialists. 

 - To undertake community based studies of the number of people with PD (prevalence) in Tanzania, Ghana, Nigeria and Kenya, testing different diagnostic methods. 

  - To develop a database of PD outpatients in sites in the different countries to enable description of their characteristics.

 - To look at the effectiveness and side-effects of preparations of Mucuna pruriens (MP), a tropical plant, compared to Levodopa (standard drug treatment) in Tanzania. 

  - To assess the response to drug treatment, with low-cost home monitoring with wearable movement sensors in PwP who consent. 

  - To work with patient and carer support groups to understand lived experience, raise public awareness via standard media techniques and social media.

  - To collaborate with the Investigators on a large genetic project to collect blood and saliva samples for genetic analyses, as well as stool samples for microbiome analysis.