Trial of Alginates in Throat Symptoms 

A Trial looking at the use of Gaviscon Advance in comparison to a Placebo (a 'dummy' treatment) as a potential treatment for persistent throat symptoms.

  • Have you been referred to Ear Nose Throat (ENT) outpatient department or Speech and Language Therapy (SaLT) clinic with persistent throat symptoms that have been ongoing for over 6 weeks?
  • Are you 18 years old or over?

You may be eligible to take part in a clinical research study investigating the effectiveness of Gaviscon Advance in managing your throat symptoms in preparation for your outpatient appointment.

About the Study

The TALGiTS study is looking at the use of Gaviscon Advance in comparison to placebo (a ‘dummy’ treatment) for the treatment of persistent throat symptoms during an 8-week treatment period prior to your first outpatient clinic appointment.

Approximately 250 people will take part in this study which will be conducted at up to 15 sites across the UK.

Who can participate?

If you have been referred to ENT or SaLT clinic with persistent throat symptoms (hoarse voice, lump in throat sensation, throat clearing, cough, post-nasal secretions / catarrh, throat discomfort) and are aged 18 or over you may be eligible to take part in the TALGiTS trial.  

What would taking part involve?

The intention is to run this trial with as much remote participant contact as possible using telephone, video consultations or any other suitable methods of contact. There is one in person clinic visit planned at the end of the trial, which is the standard clinic appointment you would have received following your referral.  You would be involved in the trial for 8-weeks.


If you think you may be eligible and are interested in taking part in this trial, please contact your GP.


The information on this website is for Trial Participants.