Renal Research

The Renal Research Group is based in Newcastle University and Newcastle upon Tyne Hospital NHS Foundation Trust. The Group focuses delivering better treatment for patients with kidney disease and is recognised as a leading centre for translation research in nephrology and transplantation.

There are several main research themes based at:

Institute of Cell and Molecular Biosciences (ICAMB)

Insitute of Cellular Medicine (ICM)

Institute of Genetic Medicine (IGM)

The research themes include:

  • The role of complement activation glomerular disease.
  • The genetic basis of cystic and other renal diseases
  • The mechanisms of chronic inflammation and fibrosis in the kidney
  • Immune mechanisms of transplant rejection
  • Ischaemia reperfusion injury and prevention of delayed graft function
  • Acute Kidney Injury


The Renal Research Group has close links with the both adult and paediatric clinical services and has an active clinical trials group, supported by research nurses, trails co-ordinators and data managers. The Group leads and recruits to many NIHR portfolio studies, with many collaborations within Newcastle, other academic institutions and with industry.