Maya Randhawa

• CDT Doctoral Researcher (Aligned) Supervisor: Dr Hannah Stewart
• Email: M.Randhawa3@newcastle.ac.uk
• Project Title: Lysine-targeted warheads to expand covalent drug discovery

Institution: Newcastle University

Project summary: Lysine is an abundant but underexplored target for covalent drug design due its reduced nucleophilicity. This project explores a dual-functionality approach for covalent modification. Using a design–make–test approach, the research aims to develop and optimise novel chemical tools for selective lysine targeting, with reactivity evaluated using model assays.