Cohort 5 (2023-2027)
William Midgley
- CDT Doctoral Researcher Supervisor: Prof Ehmke Pohl
- Email: william.h.midgley@durham.ac.uk
- Project Title: PROTACS: new methods for linker design to target EBNA1 (Eppstein-Barr nuclear antigen 1)
Institution: Durham University
Project Summary: I’m using computational techniques to help develop new methods of PROTAC linker development (a protein-targeting drug type) alongside the Cambridge Crystallographic Data Centre. I am focussing on EBNA1, a viral antigen known to be associated with certain cancers. The end goal is to develop a method to streamline PROTAC development in the future.
Interesting Fact: I play Uilleann Pipes for a local cèilidh band.