Cohort 5 (2023-2027)
Elle Watson
- CDT Doctoral Researcher Supervisor: Dr Celine Cano
- Email: E.Watson7@newcastle.ac.uk
- Project Title: Development of DNA-PK-targeting PROTACs to maximise DNA-PK blockage in advanced prostate cancer
Institution: Newcastle University
Project Summary: Organic synthesis and optimisation of established DNA-PK inhibitors. Developing an appropriate linker to attach the inhibitor to an E3 ligase protein for the synthesis of a proteolysis targeting chimeric molecule (PROTAC).
Interesting Fact: I am a member and instructor in the Newcastle University Pole and Aerial Club