Project summary: In cellular biology, intracellular phase separation has now garnered much attention as a means to organize intracellular solutions through the formation of droplet-like sub-compartments. These droplets interact with biological membranes inside cells, and as a result, the droplets and the membranes can mutually remodel their shapes and morphologies. Molecular dynamics and continuum modelling will be employed to provide a theoretical and computational frameworkfor this system, and ultimately inform ongoing in vitro experiments.