Cohort 5 (2023 - 2027)

Cohort 5 (2023 - 2027)

 

Code Project Title Supervisor Institution
mos23_16 mos23_16 PROTACS new computational methods, targets and experimental validation Ehmke Pohl  Durham
mos23_01   mos23_01 Synthetic antimicrobials based on natural toxins Tim Blower Durham
mos23_02   mos23_02 Development of a new approach to targeted chelation therapies Will Brittain Durham
mos23_03 mos23_03 DUNeS: Structure based development of dual specificity inhibitors of NLRP3 and SARM1 Agnieszka Bronowska     Newcastle     
mos23_04 mos23_04 Development of DNA-PK-targeting PROTACs to maximise DNA-PK blockage in advanced prostate cancer Celine Cano Newcastle
mos23_05 mos23_05 Identification of new molecular targets for NTDs Steven Cobb Durham
mos23_06 mos23_06 Differential diagnostics for leishmaniasis - bench to field Paul Denny Durham
mos23_07 mos23_07 Cell- and Tissue-targeted cyclic peptide discovery platform Akane Kawamura Newcastle
mos23_08 mos23_08 Ribosomal glycopeptide production to investigate glycosylation changes in prostate cancer Tom McAllister Newcastle
mos23_09 mos23_09 Structure guided approach to assay development for inhibiting Dengue virus replication Liz Morris Durham
mos23_10 mos23_10 Mass spectrometry approaches to address capability gaps in drug discovery for membrane transporters Matthias Trost Newcastle
mos23_11 mos23_11 Proteomics-based assessment of drug performance in vivo by establishing target engagement methods and characterizing new disease models Matthias Trost Newcastle
mos23_12 mos23_12 Lead optimization by DNA-encoding Mike Waring Newcastle
mos23_13 mos23_13 Expanding the Build-Couple-Transform Paradigm to develop highly diverse screening libraries for Drug Discovery Mike Waring Newcastle
mos23_14 mos23_14 CRISPR-mediated tagging of endogenous proteins for structural mapping of interactions Wyatt Yue Newcastle
mos23_15 mos23_15 DNA Nanosensors for Metal Ion Cancer Biomarkers Harold Fellerman Newcastle