Diana Jurk (ICaMB) “Senescence - can anti-inflammatories help?"
David Llobet-Navas (IGM) "Insights from miR-424/503: a breast tumour suppressor with a role in fat homeostasis"
Laura Greeves (IoN) "Mitochondrial DNA mutations in ageing and cancer"
Amanda Villalvilla (ICM) "Diving into genetic predisposition for osteoarthritis: epigenetic modulation of the 20q13 susceptibility region"
Prof. Neil Perkins (ICaMB)
"Regulation of cancer cell proliferation and survival by NF-kappaB"
Dr. Alison Day (ICaMB, Elizabeth Veal's lab)
"Why evolve peroxidases that are sensitive to inactivation by hydrogen peroxide?"
Prof. David Elliott (IGM)
"Identifying functional targets for splicing regulators"
Dr. Laura Maringele (IAH)
"CIA factors at telomeres?"
Dr. Adam Benham (School of Biological and Biomedical Sciences, Durham University)
"Why are specialised ER chaperones required for male fertility?"
Dr. Jelena Mann (ICM)
"Protective Adaptation by Heritable Epigenetic Modifications"
Dr. Fiona Oakley (Institute of Cellular Medicine)
" NF-kB signalling in wound healing and regeneration"
Dr. Luke Gaughan (Northern Institute for Cancer Research)
" Epigenetic regulation of estrogen receptor function in breast cancer cells”
Prof. Linda Lako (IGM)
"A break is not the end: insights into DNA damage disorders using pluripotent stem cells"
Dr. Ian Cowell (ICaMB)
"DNA topoisomerases and transcription factories, a recipe for chromosome translocation?"
Dr. Kelly Coffey (NICR)
"The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover”
Prof. Caroline Austin (ICaMB)
"Human genome-wide TOP2B occupancy"
Prof. Michael Briggs (IGM)
“Refining disease mechanisms in genetic skeletal disease for translational validation”
Dr. Joao Passos (IAH)
“Mitochondria, telomeres and the severity of senescence”
Sponsored by Life Technologies:
Urszula McClurg (Robson lab, NICR) "Rub a DUB Drug - exploring DUBs as therapeutic targets in prostate cancer"
Alessio Ianetti (Perkins lab, ICaMB) "Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence"
Mark Wade (Gaughan lab, NICR) "The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer"
Filippo Scialo (Sanz lab, ICaMB) "Site-specific ROS signal preserves mitochondrial function and extends Drosophila lifespan"
Olivier Binda (NICR) “Chromatin signalling"
Iaroslava Kos (Quinn lab, ICaMB) “Inhibition of Cap1-mediated oxidative stress responses – a major antifungal defence mechanism?"
David Hill (Lovat lab, ICM) "Contribution of autophagy to the survival of melanoma-initiating CD271-positive subpopulations"
Ashwin Sriram (Sanz lab, ICaMB) “A mitochondrial ROS signal activates mitophagy and regulates mitochondrial dynamics"
Caroline Wilson (Mann lab, ICM) “The role of neutrophils in inflammation driven cancer"
Elaine Willmore (NICR) "Targeting IKK alpha in primary leukaemia cells: effects on non-canonical NF-kB signalling and cell survival"
Seamus Holden (ICaMB) "Spying on the biophysics of live bacteria with super-resolution microscopy"
Graeme Hewitt (Passos/Korolchuk lab, ICaMB) "p62: linking protein homeostasis with DNA damage during ageing"
Baddiley-Clark Seminar Room (ICaMB, main campus), 11 February 2016, 3:00-5:30pm
Jelena Mann (ICM) “Epigeentic reprogramming of wound healing"
Martyna Pastok (Endicott lab, NICR) "CDK4 and CDK6 containing complexes in cell cycle regulation"
Nuria Martinez (Singh lab, ICaMB) "Autophagy and Integrative Physiology"
Clara Correia Melo (Passos lab, ICaMB) "Mitochondria are required for the pro-ageing features of cellular senescence"