2022

Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification

Gut. doi: 10.1136/gutjnl-2021-325918

2021

Convergent somatic mutations in metabolism genes in chronic liver disease

Nature. doi: 10.1038/s41586-021-03974-6

The human liver microenvironment shapes the homing and function of CD4⁺ T-cell populations

Gut. doi: 10.1136/gutjnl-2020-323771

Sorafenib is associated with a reduced rate of tumour growth and liver function deterioration in HCV-induced hepatocellular carcinoma

Journal of Hepatology. doi: 10.1016/j.jhep.2021.05.015

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Nature. doi: 10.1038/s41586-021-03362-0

Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores

Journal of Hepatology. doi: 10.1016/j.jhep.2020.11.024

TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms

Gut. doi: 10.1136/gutjnl-2019-319227

2020

Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications

Journal of Hepatology. doi: 10.1016/j.jhep.2020.03.025

Molecular classification and therapeutic targets in extrahepatic cholangiocarcinoma

Journal of Hepatology. doi: 10.1016/j.jhep.2020.03.008

Liver-resident CD8+ T cells: Learning lessons from the local experts

Journal of Hepatology. doi: 10.1016/j.jhep.2020.02.001

Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma

Journal of Hepatology. doi: 10.1002/hep.30811

2019

The landscape of gene mutations in cirrhosis and hepatocellular carcinoma

Journal of Hepatology. doi: 10.1016/j.jhep.2020.01.019

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Nature. doi: 10.1038/s41586-019-1670-9

Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival

Journal of Hepatology. doi: 10.1016/j.jhep.2019.01.028

Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage

Gut. doi: 10.1136/gutjnl-2017-314107