2019

The landscape of gene mutations in cirrhosis and hepatocellular carcinoma

Journal of Hepatology. doi: 10.1016/j.jhep.2020.01.019

 

The oncogenic role of hepatitis delta virus in hepatocellular carcinoma

JHEP Reports. doi: 10.1016/j.jhepr.2019.05.001

 

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Genes & Development. doi: 10.1101/gad.331272.119

 

A continuous-time hidden Markov model for cancer surveillance using serum biomarkers with application to hepatocellular carcinoma

Metron. doi: 10.1007/s40300-019-00151-8

 

R-spondin 2 Drives Liver Tumor Development in a Yes-Associated Protein-Dependent Manner

Hepatology Communications. doi: 10.1002/hep4.1422

 

Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure

Clinical Proteomics. doi: 10.1186/s12014-019-9257-x

 

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Nature. doi: 10.1038/s41586-019-1670-9

 

New Drugs Effective in the Systemic Treatment of Hepatocellular Carcinoma

Clinical Liver Disease. doi: 10.1002/cld.796

 

Early Experience of Trans-arterial Chemo-Embolisation for Hepatocellular Carcinoma with a Novel Radiopaque Bead

Cardiovascular & Interventional Radiology. doi: 10.1007/s00270-019-02317-3

 

Biology and significance of alpha-fetoprotein in hepatocellular carcinoma

Liver International. doi: 10.1111/liv.14223

 

An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents

Gastroenterology. doi: 10.1053/j.gastro.2019.07.028

 

Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials

British Journal of Cancer. doi: 10.1038/s41416-019-0513-7

 

Urine protein:creatinine ratio vs 24-hour urine protein for proteinuria management: analysis from the phase 3 REFLECT study of lenvatinib vs sorafenib in hepatocellular carcinoma

British Journal of Cancer. doi: 10.1038/s41416-019-0506-6

 

β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma

Cancer Discovery. doi: 10.1158/2159-8290.CD-19-0074

 

Beneficial Noncancerous Mutations in Liver Disease

Trends in Genetics. doi: 10.1016/j.tig.2019.05.002

 

Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population

Hepatic Medicine. doi: 10.2147/HMER.S193996

 

From NASH to HCC: current concepts and future challenges

Nature Reviews Gastroenterology & Hepatology. doi: 10.1038/s41575-019-0145-7

 

Notch Signaling Mediates Secondary Senescence

Cell Reports. doi: 10.1016/j.celrep.2019.03.104

 

A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices

Hepatology. doi: 10.1002/hep.30651

 

Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival

Journal of Hepatology. doi: 10.1016/j.jhep.2019.01.028

 

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Nature Medicine. doi: 10.1038/s41591-019-0379-5

 

Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas

Cell Death & Differentiation. doi: 10.1038/s41418-019-0316-7

 

Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease

Scientific Reports. doi: 10.1038/s41598-019-39998-2

 

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

Journal of Autoimmunity. doi: 10.1016/j.jaut.2019.02.001

 

Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer

Nature Communications. doi: 10.1038/s41467-019-08586-3

 

Editorial: simplifying screening for primary liver cancer - do the LCR1 and LCR2 tests hold the key?

Alimentary Pharmacology & Therapeutics. doi: 10.1111/apt.15119

 

The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers

Cellular and Molecular Gastroenterology and Hepatology. doi: 10.1016/j.jcmgh.2018.10.007

 

Weighing the benefits of hepatocellular carcinoma surveillance against potential harms

Journal of Hepatocellular Carcinoma. doi: 10.2147/JHC.S159581

 

Immune Exclusion-Wnt/CTNNB1 Class Predicts Resistance to Immunotherapies in HCC

Clinical Cancer Research. doi: 10.1158/1078-0432.CCR-18-3778

 

Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage

Gut. doi: 10.1136/gutjnl-2017-314107