2013 Participants
Oliver John Smith
Hereditary Haemorrhagic Telangiectasia (HHT) is a rare genetic disease characterised by blood vessel malformations that can result in heart failure, and bleeding that leads to anaemia. HHT affects 1 in 8000 people and is classified as a rare disease. It is now recognised that the large number of rare diseases together contribute to a large amount of disability and suffering in many patients. We have been able to model this disease in mouse, which is being used to screen new therapies for HHT patients. This project will investigate the causes of heart failure in HHT.
Funding source: Wellcome Trust