STICH 2 Trial - Criteria

Inclusion / Exclusion Criteria

Consider patients presenting within 48 hours of a Spontaneous Lobar Intracerebral Haemorrhage (ICH) where there is equipoise about the relative risks / benefits of surgery.

Inclusion Criteria

  • Spontaneous lobar ICH on CT scan (1cm or less from cortex surface of the brain) within 48 hrs of ictus
  • Best MOTOR score on GCS of 5 or 6 and best EYE score on the GCS of 2 or more.
  • Volume of haematoma between 10 and 100ml [using Broderick Method (axbxc)/2]


  • Exclusion Criteria
  • Clear evidence that the haemorrhage is due to an aneurysm, tumour, trauma, or angiographically proven arteriovenous malformation (AVM).
  • Intraventricular haemorrhage.
  • Hydrocephalus
  • Brain stem/ cerebellar/ basal ganglia /thalamic haemorrhage or extension of the lobar haemorrhage into any of these areas.
  • Severe pre-existing physical or mental disability or severe co-morbidity.
  • If surgery cannot be performed within 12 hrs
  • Unreversed clotting or coagulation problems


  • Last updated 20 Mar 2007
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