NCTU
Newcastle Neurosurgery Clinical Trials Unit

Neurosurgical Clinical Trial Unit
Neurosurgical Clinical Trial Unit - RescueICP

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Rescue ICP

RESCUE ICP

International multicentre, prospective, randomised controlled trial on the role of decompressive craniotomy in management of severe head injury.

RescueICP aims to determine the effectiveness of an operation (decompressive craniectomy), compared to medical management alone, to treat brain swelling and improve outcome following traumatic brain injury.


Brief inclusion / exclusion criteria

Inclusion:

  • Patients aged 10-65 years old
  • Abnormal CT and requiring ICP monitoring
  • Raised ICP (>25mmHg for <1-12 hours)

  • Exclusion:

  • Patients with bilateral fixed and dilated pupils
  • Unable to monitor ICP
  • Patients who have received barbiturates prior to randomisation
  • Where there is brainstem involvement
  • Moribund condition on admission
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    Staff Involved

    Principal Investigators:

    Prof. P. Hutchinson
    Prof. P. Kirkpatrick

    Prof. A.D. Mendelow

    		 Assigned Registrar:

    Associated Staff:    		 Mr. D. Holliman

    Dee Frost

    brain

    Last updated 29 Jan 2008
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