NCTU
Newcastle Neurosurgery Clinical Trials Unit

Neurosurgical Clinical Trial Unit
Neurosurgical Clinical Trial Unit - ISAT

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ISAT

ISAT
IN FOLLOW UP

A randomised trial of surgery compared to endovascular therapy in the treatment of ruptured intracranial aneurysms.

ISAT is a multicentre prospective randomised clinical trial comparing neurosurgical clipping and endovascular coil treatment for patients with a ruptured cerebral aneurysm causing acute subarachnoid haemorrhage.

Brief inclusion / exclusion criteria








Inclusion:

  • ASAH (as indicated by CT scan or lumbar puncture and an intracranial aneurysm confirmed by computer tomographic or conventional angiography)
  • Patient randomised within 48 hours of ictus

    • Exclusion:

  • Pregnancy
  • Major renal, hepatic or pulmonary disease
  • Major cardiac disease or recent myocardial infarct (< 6 months)
  • Age less than 18 years
  • Moribund condition on admission
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    Staff Involved

    Principal Investigators:

    Dr Andrew Molyneux (Oxford)
    Mr Richard Kerr

    Prof. A.D. Mendelow

    		 Assigned Registrar:

    Associated Staff:

    IMASH

    Last updated 29 Jan 2008
    © NCTU