Neurosurgical Clinical Trial Unit

ACST-2 ARUBA BACKSWING CLEAR IVH EFALL ICSS ISAT ISUIA NEWFORM RESCUE ICP STASH STICH II SUDEN TOPSAT

Mission Statement: "To promote evidence-based neurosurgery through high-quality research, education and publication." • Evidence-based Neurosurgery • Useful Information and Guidelines • Training Days

Location:

3-4 Claremont Terrace Newcastle University Newcastle upon Tyne NE2 4AE Tel : +44 (0)191 222 5761 Fax: +44 (0)191 222 5762

Staff
	Consultant Neurosurgeons	Specialist Registrars	Associated Staff
	Mr. J. Crossman Mr. M. Davis Mr. C.J. Gerber Mr. A. Jenkins Prof. A. D. Mendelow Mr. P. Mitchell Mr. J.J. Nissen Mr. B. Parameswaran Mr. N. Ross Mr. N. Todd Mr. G. Wynne-Jones	Dr. O. Adeniyi Dr. E. Blount Dr. A. Borah Dr. R. Dubey Dr. D. Holliman Dr. I. Ibbett Dr. M. Lazukova Dr. E. Magzoub Dr. N. Mukerji Dr. o. Ojo Dr. A. Paluzzi Dr. p. Panaretos Dr. A. Penalosa Dr. S. Rajeev Dr. A. Solth Dr. F. Vergani Dr. y. Yoongkhong	Dr. B. Gregson Dr. E. Rowan Dr. A. Andras Dr. Z. Liao Dr. M. Baghaat Miss G. Kenyon Miss H. Atkinson Mr. C. Cowie Ms. Bianca Tobin (Research Nurse)

click on the logo to go to the relevant trial webpage
	ACST-2 - asymptomatic carotid stenosis International multi-centre randomised trial to determine whether surgery (CEA) in patients with asymptomatic disease reduces the risk of stroke when compared to stenting.
	ARUBA - Brain arteriovenous malformations (BAVMs) International randomised trial to compare intervention and conservative treatment in patients with unruptured brain arteriovenous malformation (BAVM).
NO LONGER RECRUITING	BACKSWING - Discogenic disease Randomised controlled trial of inversion therapy in patients with pure single level discogenic disease with the aim of reducing the need for surgery.
NOT CURRENTLY RECRUITING	Clear-IVH - Intraventricular haemorrhage International, multi-centre randomised controlled trial investigating rt-PA as a treatment for intraventricular haemorrhage thromobolysis.
	EFALL - Epidural fentanyl analgesia following laminectomy Randomised controlled trial to determine whether epidural fentanyl given during a lumbar laminectomy is effective at controlling post-operative pain compared to standard analgesia.
	ICSS - Symptomatic atheromatous carotid stenosis An international, multicentre, randomised, controlled, open, prospective clinical trial evaluating primary stenting of carotid artery stenosis in patients with symptomatic disease in comparison to endarterectomy.
IN FOLLOW UP	ISAT - Subarachnoid haemorrhage A multicentre prospective randomised clinical trial comparing neurosurgical clipping and endovascular coil treatment for patients with a ruptured cerebral aneurysm causing acute subarachnoid haemorrhage.
IN FOLLOW UP	ISUIA - Unruptured intracranial aneurysm Cohort study to define the long-term risks of UIA rupture and other UIA natural history outcomes.
	NEWFORM - Cervical radiculopathy Pilot study comparing anterior cervical discectomy and fusion (ACDF) and posterior foraminotomy as surgical interventions for cervical radiculopathy.
	RESCUE ICP - Severe head injury International multicentre, prospective, randomised controlled trial on the role of decompressive craniotomy in management of severe head injury.
	STASH - aneurysmal subarachnoid haemorrhage Multicentre placebo-controlled double-blinded phase II trial assessing the clinical benefits of simvastatin in aneurysmal subarachnoid haemorrhage.
	STICH II - superficial supratentorial lobar haematomas International multi-centre trial to evaluate the role of early surgery in superficial supratentorial lobar haematomas without intraventricular haemorrhage.
	SUDEN - Traumatic raised intracranial pressure in children A randomised clinical trial of surgical decompressive craniectomy for the control of traumatic raised intracranial pressure in children.
	TOPSAT - Treatment of Poor-grade Sub-arachnoid haemorrhage Trial A pilot study, based in Newcastle, randomising patients with WFNS grades IV and V comparing early (<24hours) or late endovascular treatment.
	Last updated 27 June 2011 © NCTU Email: NCTU@ncl.ac.uk