Newcastle University

Our research interest focuses on two areas: 1) keratinocyte stem cell regulation in normal and psoriatic skin, and 2) the development of gene therapies for blistering skin diseases aiming to treat patient’s keratinocyte stem cells ex vivo using the novel TALE nuclease technology. Furthermore, we have a strong background in intermediate filament research and contributed to the understanding of the role of intermediate filaments under physiological conditions and in disease.

The lab is part of the Institute for Cellular Medicine (Department of Dermatological Sciences) in the Medical School at Newcastle University.