About PROACT
A multi-centre, prospective, randomised, open-label, blinded end-point, superiority trial to test the effectiveness of Enalapril (ACE inhibitor) in preventing cardiotoxicity in patients with breast cancer and lymphoma undergoing anthracycline chemotherapy
Full Title: Preventing cardiac damage in patients treated for breast cancer and lymphoma: a phase 3 Randomised, Open label, blinded endpoint, superiority trial of enalapril to prevent Anthracycline-induced CardioToxicity (PROACT).
Lay Title: PROACT: Can we prevent chemotherapy-related heart damage in patients with breast cancer and lymphoma?
Trial Identifiers:
ClinTrials.gov: NCT03265574
EudraCT: 2017-001094-16
IRAS ID: 213348
Start date:
September 2017
End of recruitment:
March 2023
Funder:
National Institute of Health Research – Research for Patient Benefit Programme (project reference PB-PG-0815-20061)
Chief Investigator:
Dr David Austin
The James Cook University Hospital
South Tees Hospitals NHS Foundation Trust
Marton Road
Middlesbrough
TS4 3BW
Sponsor:
South Tees Hospitals NHS Foundation Trust
Clinical Trials Unit:
Newcastle Clinical Trials Unit, Newcastle University
Tel: 01642 854 638