Molecular and Cellular Evolution of Microbial Eukaryotes
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Newcastle
EMBO World 09
Molecular Evolution Workshop 2010
Trachipleistophora hominis

Dr. Alison Gregory

Contact information

  • Phone number: +44 (0)191 222 3481
  • e-mail adress: Alison.Gregory (at) ncl.ac.uk

Work description

I am currently working on a project to characterise the nucleotide transport (NTT) proteins used by the microsporidian parasite, Trachipleistophora hominis. I am also working on a project to identify how the mitosomes of the diplomonad parasite, Giardia lamblia acquire ATP.

I completed my PhD at the University of St Andrews, Scotland, where I studied a viral disease (a reovirus) of crustaceans (swimming crabs). I successfully developed a primary cell culture system for crustacean haemocytes and developed an in situ hybridisation method to detect virus in infected tissues. After my PhD, I joined the Marine Laboratory in Aberdeen where I worked on economically important viral pathogens that impact the aquaculture industry, in particular infectious salmon anaemia virus (ISAV) and infectious pancreatic necrosis virus (IPNV). I conducted genetic analysis of birnaviruses and developed a range of methods to detect viruses in environmental samples for epidemiological investigations.

Alison's publications

  • Green DM, Gregory A, Munro LA. Small- and large-scale network structure of live fish movements in Scotland. Preventiative Veterinary Medicine. vol 91 p. 261-9 (2009). pubmed
  • Munro LA, Gregory A. Application of network analysis to farmed salmonid movement data from Scotland. Journal of Fish Disease. vol 32 p. 641-4 (2009). pubmed
  • Bain N, Gregory A, Raynard RS. Genetic analysis of infectious pancreatic necrosis virus from Scotland. Journal of Fish Disease. vol 31 p. 37-47 (2008). pubmed
  • Gregory A, Munro LA, Snow M, Urquhart KL, Murray AG, Raynard RS. An experimental investigation on aspects of infectious salmon anaemia virus (ISAV) infection dynamics in seawater Atlantic salmon, Salmo salar L. Journal of Fish Disease. vol 32 p. 481-9 (2008). pubmed
  • Urquhart KL, Murray AG, Gregory A, O'Dea M, Munro LA, Smail DS, Shanks AM, Raynard RS. Estimation of infectious dose and viral shedding rates for infectious pancreatic necrosis virus in Atlantic salmon, Salmo salar L., post-smolts. Journal of Fish Disease. vol 31 p. 879-887 (2008). pubmed
  • Wallace IS, Gregory A, Murray AG, Munro ES, Raynard RS. Distribution of infectious pancreatic necrosis virus (IPNV) in wild marine fish from Scottish waters with respect to clinically infected aquaculture sites producing Atlantic salmon, Salmo salar L. Journal of Fish Disease. vol 31 p. 177-186 (2008). pubmed
  • Gregory A, Munro LA, Ostergard PS, Raynard RS. The importance of applying confirmatory tests to diagnose the presence of infectious salmon anaemia virus (ISAV) in environmental samples by RT-PCR. Bulletin of the European Association of Fish Patho. vol 27 (2007).
  • Gregory A, Munro LA, Wallace IS, Bain N, Raynard RS. Detection of infectious pancreatic necrosis virus (IPNV) from the environment in the vicinity of IPN-infected Atlantic salmon farms in Scotland. Journal of Fish Diseases. vol 30 p. 621-630 (2007). pubmed
  • Wallace IS, Gregory A, Munro ES, Bain N, Raynard RS. Infectious pancreatic necrosis virus (IPNV) isolated from hake, Merluccius merluccius, from Scotland. Bulletin of the European Association of Fish Patho. vol 25 p. 86-90 (2005).
  • Snow M, Raynard RS, Murray AG, Bruno DW, King JA, Grant R, Bricknell IR, Gregory A. An evaluation of current diagnostic tests for the detection of infectious salmon anaemia virus (ISAV) following experimental water-borne infection of Atlantic salmon, Salmo salar L. Journal of Fish Diseases. vol 26 p. 135-146 (2003). pubmed
  • Cunningham CO, Gregory A, Black J, Simpson I, Raynard RS. A novel variant of the infectious salmon anaemia virus (ISAV) haemagglutinin gene suggests mechanisms for virus diversity. Bulletin of the European Association of Fish Patho. vol 22 p. 366-374 (2002).
  • Gregory A. Detection of infectious salmon anaemia virus (ISAV) by in situ hybridisation. Diseases of Aquatic Organisms. vol 50 p. 105-110 (2002). pubmed
  • Raynard RS, Murray AS, Gregory A. Infectious salmon anaemia virus in wild fish from Scotland. Diseases of Aquatic Organisms. vol 46 p. 93-100 (2001). pubmed
  • Walton A (Gregory A) and Smith VJ. Primary culture of the hyaline haemocytes from marine decapods. Fish and Shellfish Immunology. vol 9 p. 181-184 (1999).
  • Walton A (Gregory A), Montanie H, Arcier JM, Smith VJ, Bonami JR. Construction of a gene probe for detection of P virus (Reoviridae) in a marine decapod. J Virol Methods. vol 81 p. 183-92 (1999). pubmed