This study is the first enhanced laryngeal cancer disease cohort. We aim to deliver a prospective cohort study of a minimum of 150 patients recruited over a 3-year period. This initial phase of the study will recruit patients from eight head and neck cancer centres in the North of England: Newcastle, Liverpool, Sunderland, Middlesbrough, Hull, Sheffield, Leeds and Manchester. Once established, in future research, we aim to roll out the cohort nationally.

This study will be pragmatic, involving patients with laryngeal cancer attending hospital as part of their routine care. Patients will be identified by a member of the research team and recruitment will be supported by the research team, all of whom will be trained in Good Clinical Practice and consent.

Eligibility criteria

Inclusion criteria

• Suspected but unconfirmed laryngeal cancer (Group 1)
• Confirmed new diagnosis of laryngeal cancer (Group 2)
• Age over 18
• Capacity to consent
• Ability to understand written and spoken English

Exclusion criteria

• Recurrence or second head and neck primary cancer