Human Dendritic Cell Laboratory

The Human Dendritic Cell Lab is based at the Institute of Cellular Medicine, Newcastle University. Dendritic cells are the sentinels and orchestrators of immune responses and the focus of our research is to understand where they come from and how they work in living humans.  Our work is relevant to infectious diseases, transplantation and cancer medicine.  We have a special interest in patients with dendritic cell deficiency and histiocytosis.

Newcastle Adult Histiocytosis Clinic


More information about the clinic available here


Find us on Twitter @HumanDCLab


08.04.19 Dendritic cell development publication available on Sneak Peek

Our most recent publication titled "Differential IRF8 Requirement Defines Two Pathways of Dendritic Cell Development in Humans" is now available on Sneak Peek! Read it here:

Last modified: Mon, 08 Apr 2019 14:48:34 BST

25.03.19 Flt3 paper pre-published on bioRxiv

Our most recent paper describes a simple blood test to monitor response to treatment in acute myeloid leukaemia. Read it here:

Last modified: Mon, 08 Apr 2019 14:41:53 BST

15.10.18 Welcome to Jason Lam, our new PhD student!

Jason will be working on mapping the induction of allo-immune effector cells in haematopoietic stem cell transplantation under the supervision of Prof Matt Collin.

Last modified: Wed, 19 Dec 2018 15:39:48 GMT

17.04.18 HuDC lab away day

DC lab away day!

Last modified: Tue, 09 Apr 2019 11:58:26 BST

27.03.18 Ikaros family zinc finger 1 publication

Cytlak et al Ikaros family zinc finger 1 regulates dendritic cell development and function in humans. Read Nature Comms publication here

Last modified: Fri, 27 Apr 2018 12:37:45 BST

27.02.18 Congratulations to our alumnus Dr Kile Green!

Kile recently completed his PhD with the Human DC lab. His research focused on the transcriptomics of dendritic cell subsets and was funded by Bright Red.

Last modified: Thu, 08 Mar 2018 14:00:32 GMT

03.01.18 Latest update on human dendritic cells in Immunology

Read the article here:

Last modified: Fri, 27 Apr 2018 12:31:16 BST

01.09.17 Welcome to Fareeha Tariq, our new PhD student!

Fareeha will be working on the identification of somatic mutations in rheumatoid arhritis, under the supervision of Prof Matt Collin and Dr Amy Anderson. Her project is funded by the British Research Council.

Last modified: Thu, 22 Feb 2018 11:35:21 GMT

01.06.17 Welcome to Dr Preeti Singh, our new research associate!

Preeti's research will be focusing on granulomatous disease and is funded by the Medical Research Council.

Last modified: Thu, 22 Feb 2018 11:52:37 GMT