Participants

Elisha Dhillon

  • Design of Stealth Polymeric Nanoparticles
  • Master of Pharmacy with Honours

Encapsulating drugs in delivery systems, such as nanoparticles, is a way to improve drug administration whilst bettering patient receptibility and reducing experienced side effects. There are issues with this technology currently, such as eradication of the nanoparticles by the immune system, inflammatory responses, and early elimination of the drug by the body. This research explores new strategies to adapt nanoparticle surfaces with polymers, in order to prevent immunological responses and therefore, removal of the drug and its delivery system from the body. This project will involve nanoparticle engineering, analysis of its characteristics and its effectiveness as a drug delivery system, via instrumental techniques such as dynamic light scattering (DLS), nanoparticle tracking analysis and Ultra-Violet detection.

 

Funded by: Newcastle University Research Scholarship

Project Supervisor: Professor Moein Moghimi