Participants
Debora Alvim
Hearing loss is a significant risk factor for Alzheimer's disease dementia, the most common type of dementia characterised by protein accumulation, brain damage, and cognitive decline. This study investigates the relationship between hearing loss and Alzheimer's disease using computational analysis of neuroimaging data from MRI scans and central hearing test outcomes.
The research aims to uncover shared mechanisms between hearing loss and Alzheimer's disease, potentially leading to innovative prevention and early detection strategies. Cross-sectional analysis demonstrates a strong link between hearing-related cognitive performance and neurodegeneration markers in Alzheimer's disease. This suggests that Alzheimer's pathology, particularly in the Medial Temporal Lobe, may affect central hearing.
This observation is crucial, hinting that central hearing loss might be an early indicator of Alzheimer's disease. Early identification is vital in managing Alzheimer's, making this research promising for understanding and managing this condition.
Funded by: Newcastle University Summer Research Programme
Project Supervisor: Meher Lad