Adam Gardner

• Mpharm Pharmacy
• The identification and synthesis of novel allosteric integrase inhibitors

This research is being carried out to enhance the lives of those with HIV/AIDS. The study involves developing a drug that can enter the body and prevent the action of a specific enzyme within the virus. Inhibition of the enzyme will results in the virus being unable to replicate. Although medications in the past have been developed that can stop viral replication this drug will be unique since the bespoke mode of action will prevent any virus in the body forming a resistance to the medication. The drug will therefore be effective 100% of the time. A safe and reliable medication, to be taken every day, with the aim of prevention as treatment reducing the numbers affected by HIV/AIDS.

Funding source: Newcastle University

Supervisor: Dr Mark Ashton