Toby Middlebrook

• BSc (Hons) Physics
• Biophotonics – Exploring photonic devices for use in optogenetic stimulation of neural tissue.

Epilepsy is a neurological disorder which can be characterized by unpredictable seizures. Whilst anti-seizure medication can help people suffering from epilepsy, for many people diagnosed with epilepsy, anti-seizure medication does not work. The aim of the research project was to help explore the viability of optogenetic devices that stimulate the neural systems as an alternative to anti-seizure medication. An optogenetic device is a device that uses light to stimulate or inhibit neural circuits. Within this research project, my aim was to develop computer models that can be used to simulate the properties of this device and to run an experiment using a degradation test rig that was used to test the conditions required for the device to no longer function.

Funding source: Newcastle University

Supervisor: Dr Patrick Degenaar