Steven Tan Heng Sern

• MBBS (NUMed Malaysia)
• Acute Kidney Injury in Cardiac Surgery and Transplantation: Long Term Effects and Use of Novel Biomarkers

Acute Kidney Injury (AKI) has been a common side effect and an unsolved problem for both cardiac and lungs surgeries. AKI is normally due to drugs, anaesthetic and surgical injuries during pre-, peri- and post-operation. If patients with AKI achieved a specific threshold of blood creatinine, i.e. >200 µmol/L, they usually require the Continuous Veno-Venous Haemofiltration (CVVH) program. It is a short term treatment used in ICU patients with acute or chronic renal failure to lower and maintain the blood creatinine. However, even the linkage of AKI to chronic kidney injury (CKD) is proved on cardiac and lungs surgeries, it is not well studied for transplantation. Therefore, our study aims to find the linkage for AKI leading to CKD in patients after cardiac and lungs transplantations, in order to assist further studies for prognosis of transplanted patients.

Funding source: Newcastle University

Supervisor: Prof John Dark