Yuen Nam Fan

• MSci Biomedical Sciences
• Modulation of the innate immune response by exosomes in colorectal cancer

A key survival mechanism for cancer cells is the ability to escape recognition by the immune system.  It is already known that immune cells in the vicinity of cancers behave differently to those activated in response to tissue injury or infection.  One mechanism through which cancers may modify the behaviour of immune cells is through the excretion of small particles known as exosomes which contain a variety of molecules able to modify gene expression in the immune cells around tumours.  The aim of this project is to identify how exosomes might affect the response of immune cells to colorectal tumours.

Project Supervisor: Mr Stuart Robinson, Institute of Cellular Medicine

Funding Source: Newcastle University