Lauren Yuk Ying Cheung

• BSc (Hons) Biology (Cell & Molecular Biology)
• A new chromosome modification in cell division

The Higgins laboratory studies mechanisms that bring about cell division in humans. Successful cell division requires the accurate replication and sorting of chromosomes into daughter cells, and the ability to “remember” how genes are programmed into “on” and “off” states. Errors in these processes underlie birth defects and may contribute to cancer. The Higgins group has discovered that modifications of chromosomes (i.e. phosphorylation of histones) are key regulators of these events. In this project we will carry out the first critical steps in understanding how a newly discovered histone phosphorylation influences cell division.

Project Supervisor: Professor Jonathan Higgins, Institute for Cell & Molecular Biosciences
 
Funding Source: Newcastle University